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Efficacy and safety of thalidomide in choroidal neovascular membrane model Rats

Efficacy and safety of thalidomide in choroidal neovascular membrane model Rats
沙利度胺对大鼠脉络膜新生血管膜模型的疗效和安全性
批准号:
23791967
负责人:
HAGIWARA Akira
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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英文摘要
To evaluate the safety of thalidomide for retina, we examined electroretinogram(ERG) in rats before and 7 days after injection of thalidomide in vitreous. ERG response of the rats after injection of thalidomide was not significant different from that of the rats before injection. This result suggests that the injection of thalidomide in vitreous is not toxic for retina of rats.
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