Development of procedures to prepare monoclonal plastic antibodies

在这项研究中，我们的目标是建立制备与目标肽相互作用的均一聚合物配体的程序。我们首先确定了聚合物配体上捕获目标肽蜂毒素的最小数量和结合的官能团。接下来，我们展示了通过亲和纯化过程可以分离出与蜂毒素有很强亲和力的聚合物。作为最后一步，制备了嵌段共聚物文库，并指定了捕获蜂毒素的最佳序列。

In this research, we aimed to establish procedures to prepare uniform polymer ligands that interact with target peptide. We first identified the minimum number and combination of functional group on the polymer ligands to capture target peptide melittin. We next showed that polymers with strong affinity to melittin can be isolated by affinity purification procedure. As a final step, library of block copolymers were prepared and optimum sequence to capture melittin was assigned.