Enzymatic oxidation reactions using clustered liposomes that specifically response to shear flow and temperature change

封闭的磷脂双层（脂质体）的膜特性可以通过相对较小的温度变化和由生物反应器中的流动和混合条件产生的剪切应力来改变。脂质体的这些膜性质是基于其组成、大小和聚集特性来调节的。基于所获得的结果，使用悬浮在生物反应器中的各种类型的含酶脂质体开发了催化氧化反应系统，其中酶的稳定性和反应性可以被广泛地调节。

The membrane properties of closed phospholipid bilayers (liposomes) could be altered by relatively small changes in temperature and shear stress generated by the flow and mixing conditions in bioreactors. These membrane properties of liposomes were regulated based on their composition, size and clustering characteristics. Based on the results obtained, the catalytic oxidation reaction systems, where the stability and reactivity of enzymes could be widely regulated, were developed using various types of enzyme-containing liposomes suspended in a bioreactor.