Environmental Control for Rapid Production of an Influenza VaccineAntigen using Plants

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Effects of plant growing conditions such as physical environment on the level of recombinant influenza hemagglutinin accumulation were investigated in a viral vector-based transient gene expression system. We found that air temperature post viral-vector inoculation was an important environmental variable for enhancing hemagglutinin productivity. We also suggested that vacuum infiltration of plant aerial parts can be improved for increasing the efficiency of vector inoculation.