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Evaluation between gene-polymorphism and efficacy of therapy for pulmonary arterial hypertension using next-generation DNA analysis system

Evaluation between gene-polymorphism and efficacy of therapy for pulmonary arterial hypertension using next-generation DNA analysis system
利用新一代DNA分析系统评价基因多态性与肺动脉高压治疗效果
批准号:
23791144
负责人:
SUGIMOTO Masaya
金额:
$2.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

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中文摘要
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英文摘要
We studied pulmonary arterial hypertension in children with congenital heart disease. Serum high sensitivity cTnI levels significantly correlated with Pp/Ps in children. The Qs and Qp/Qs obtained by MRI strongly correlated with those obtained by catheterization, and a significant correlation was observed between the MCFR and Pp/Ps. Moreover, unlike patients with regressed CALs (coronary arterial lesion) in Kawasaki Disease, patients with persistent CALs have abnormal mechanical properties and hemodynamics of the pulmonary artery.
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会议论文
先天性心疾患患者における肺高血圧の評価に血中高感度心筋トロポニンI とT はどちらが優れているか
血液高敏心肌肌钙蛋白 I 和 T 哪个更适合评估先天性心脏病患者的肺动脉高压?
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [杉本昌也, 梶野浩樹, 東寛]
通讯作者: 東寛
DOI: 10.1253/circj.cj-10-1211
发表时间: 2011-09-01
期刊: CIRCULATION JOURNAL
影响因子: 3.3
作者: [Sugimoto, Masaya, Ota, Kei, Kajino, Hiroki]
通讯作者: Kajino, Hiroki
DOI: 10.1016/j.amjcard.2011.11.062
发表时间: 2012-04
期刊: The American journal of cardiology
影响因子: --
作者: [M. Sugimoto;H. Ishido;M. Seki;S. Masutani;Akiko Tamai;H. Senzaki]
通讯作者: M. Sugimoto;H. Ishido;M. Seki;S. Masutani;Akiko Tamai;H. Senzaki
小児内科・43 増刊号
小儿内科/43特刊
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Hino-Fukuyo N Uematsu M, Tsuchiya S., 内山徹, 杉本昌也,梶野浩樹]
通讯作者: 杉本昌也,梶野浩樹
17
    Non-invasive evaluation of the pulmonary hypertension and inhibition of pulmonary vascular remodeling by bosentan.
    • 批准号:
      20790716
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.33万
    • 财政年份:
      2008
    • 负责人:
      SUGIMOTO Masaya
    • 依托单位:
    海外基金