A study on the kinetics of bradykinin and cytokines in the low volume hemofilter with blood priming

在新生儿血液净化治疗中，体外循环是由库血启动的。IL-6、IL-1β、TNF-α等促炎细胞因子在库红细胞和5%白蛋白混合液中浓度较低。使用聚磺酸膜和聚甲基丙烯酸甲酯膜时，这些浓度也没有变化。透析20分钟以上，使预充血中钠、钾、钙、葡萄糖、乳酸和碳酸氢盐浓度恢复正常。

In blood purification therapy for neonates, the extracorporeal circuit is primed by banked blood. Proinflammatory cytokines included IL-6, IL-1beta and TNF-alpha were low concentration in the primed blood mixed by banked red cell and 5% albumin. Also, these concentrations were no change using with polysulfon membrane or polymethyl methacrylate membrane. The concentration of sodium, potassium, calcium, glucose, lactate and bicarbonate in the primed blood were normalized by dialysis more than for 20 minites.