Clinical Application of Echocardiographic Blood Flow Visualization System

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Dissipative energy loss (EL) of the left ventricular intracavitary blood flow can be obtained using VFM analysys, a novel echocardiographic technology. EL reflects the efficiency of the blood flow, and would be an index of cardiac function. The aim of this research project was to establish the normative value of EL in children.We revealed that both the systolic and diastolic EL had a negative correlation with age and a positive correlation with HR. In addition, the diastolic EL was positively correlated with the E wave peak velocity. We derived the regression equations, in which the systolic EL was predicted by age and heart rate, and the diastolic EL was predicted by age, HR, and E wave peak velocity. Although the clinical implications of EL within the LV in the assessment of cardiac function are currently unclear, our study provides reference values for systolic and diastolic EL that can be used by future studies examining patients with various heart diseases.