Development of novel methods for identifying antibiofilm agents against multidrug-resistant Acinetobacter baumannii

鲍曼不动杆菌是一种日益重要的医院内病原体，可引起广泛的感染，尤其是在住院患者中。本研究旨在建立预防和治疗多重耐药鲍曼不动杆菌生物被膜的新策略。通过在活体模型中的应用，我们发现了治疗由多重耐药鲍曼不动杆菌引起的生物被膜感染的可能方法。需要进一步的研究来利用实时成像来建立新的模型。

Acinetobactor baumanniiis an increasingly important nosocomial pathogen that causes a broad array of infections, particularly in hospitalized patients. This study was aimed at establishing new strategies for prevention and therapy of multidrug-resistant A. baumanniibiofilms. By using in vitroa n d in vivomodels, we found possible therapeutic approaches for treating biofilm infections caused by multidrug-resistant A. baumannii. Further studies were needed to establish novel models by using real-time imaging.