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Passive smoking-induced epigenetic regulation in tooth・periodontal tissue-associated genes.

Passive smoking-induced epigenetic regulation in tooth・periodontal tissue-associated genes.
被动吸烟诱导的牙齿·牙周组织相关基因的表观遗传调控。
批准号:
23659975
负责人:
KITAMURA Masahiro
金额:
$2.25万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
In this study, we established the mouse model of experimental periodontitis similar to human periodontal lesion and investigated the effects of cigarette smoke constituents for pathogenesis of periodontal diseases using this model. In result, we found that intraperitoneally administration of nicotine or cigarette smoke condensate accelerated alveolar bone loss in mice compared with control group. These results indicate the useful animal model to examine the effects of smoking for oral diseases in human.
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会议论文
Periodontal Regeneration and FGF-2
牙周再生和 FGF-2
DOI: --
发表时间: 2013
期刊: Inflammation and Regeneration
影响因子: 8.1
作者: [Kojima Y, Yanagita M, Yamada S, Kitamura M and Murakami S]
通讯作者: Kitamura M and Murakami S
Mini-review : Periodontal regeneration and FGF-2
小回顾:牙周再生和 FGF-2
DOI: --
发表时间: 2013
期刊: Inflammation and Regeneration
影响因子: 8.1
作者: [Kojima Y, Yanagita M, Yamada S, Kitamura M, Murakami S]
通讯作者: Murakami S
DOI: 10.1111/j.1600-0722.2012.00992.x
发表时间: 2012-10
期刊: European journal of oral sciences
影响因子: 1.9
作者: [M. Yanagita;K. Mori;R. Kobayashi;Y. Kojima;M. Kubota;K. Miki;S. Yamada;M. Kitamura;S. Murakami]
通讯作者: M. Yanagita;K. Mori;R. Kobayashi;Y. Kojima;M. Kubota;K. Miki;S. Yamada;M. Kitamura;S. Murakami
Supportive periodontal therapyの長期的効果の検討
检查支持性牙周治疗的长期效果
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [山羽聡子, 北村正博, 島美和子, 久保田実木子, 坂口香穂里, 西村誠ら]
通讯作者: 西村誠ら
8
    A Challenge to the expansion of indications in periodontal tissue regeneration using FGF-2 by analyzing cross talk between signal molecules
    • 批准号:
      23390452
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $12.31万
    • 财政年份:
      2011
    • 负责人:
      KITAMURA Masahiro
    • 依托单位:
    The establishment of a new periodontal tissue regeneration therapyusing adipose-tissue derived stem cells
    • 批准号:
      18390559
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.1万
    • 财政年份:
      2006
    • 负责人:
      KITAMURA Masahiro
    • 依托单位:
    Molecular-biological analysis by DNA microarray for diagnosis of occlusal trauma
    • 批准号:
      15390646
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.34万
    • 财政年份:
      2003
    • 负责人:
      KITAMURA Masahiro
    • 依托单位:
    MULTIPLE ANALYSIS OF PERIODONTAL LESIONS BY DIFFERENTIAL DISPLAY
    • 批准号:
      13672185
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.98万
    • 财政年份:
      2001
    • 负责人:
      KITAMURA Masahiro
    • 依托单位:
    海外基金