Oral care-induded activation and reproduction of the neurocognitive function in the elderly

在这项研究中，我们使用迷你精神状态检查（MMSE）和kana-hiroi测试（KHT）来调查刷牙（TB）对神经认知的影响。采用功能磁共振成像（fMRI）技术，随机选取13名神经系统健康的受试者参与实验。当使用MMSE和KHT测试的分数在存在和不存在结核病之间进行比较时，我们发现结核病导致所有测试的分数显着增加。在MMSE和KHT中，这种效应明显依赖于年龄。此外，在使用功能磁共振成像的实验中，在TB存在的情况下，KHT表现期间前额叶皮层的激活显着增加。这些结果表明，结核病通过激活前额叶皮层对老年人的神经认知功能产生增强作用。

In this study, we investigated the involvement of toothbrushing(TB) in neurocognition, using mini-mental state examination (MMSE) and kana-hiroi test (KHT). Neurologically healthy subjects were used, of which 13 subjects were randomly selected to participate in the experiment using a functional magnetic resonance imaging(fMRI). When the scores in the tests using MMSE and KHT were compared between in the presence and absence of TB, we found that TB causes significant increases in the score of all tests. In MMSE and KHT, this effect was apparently age-dependent. Furthermore, in the experiment using fMRI, an activation of the prefrontal cortex during performance of KHT was markedly increased in the presence of TB. These results suggest that TB causes an enhancing effect on the neurocognitive function in the elderly through activation in the prefrontal cortex.