Investigation on mechanism for expansion of GM-CSF autoantibody by next generation sequencing.
Investigation on mechanism for expansion of GM-CSF autoantibody by next generation sequencing.
批准号:
24390208
负责人:
NAKATA Koh
金额:
$9.98万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2015-03-31
中文摘要
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英文摘要
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Low concentrations of recombinant granulocyte macrophage-colony stimulating factor derived from Chinese hamster ovary cells augments long-term bioactivity with delayed clearance in vitro
源自中国仓鼠卵巢细胞的低浓度重组粒细胞巨噬细胞集落刺激因子可增强长期生物活性并延迟体外清除
DOI:
10.1016/j.cyto.2014.03.009
发表时间:
2014
期刊:
Cytokine
影响因子:
3.8
作者:
[Hashimoto A, Tanaka T, Itoh Y, Yamagata A, Kitamura N, Tazawa R, Nakagaki K, Nakata K.]
通讯作者:
Nakata K.
Runx1 deficiency in CD4+ T cells causes fatal autoimmune inflammatory lung disease due to spontaneous hyperactivation of cells.
CD4 T 细胞中的 Runx1 缺陷会因细胞自发过度激活而导致致命的自身免疫性炎症性肺病。
DOI:
10.4049/jimmunol.1102991
发表时间:
2012
期刊:
J Immunol.
影响因子:
--
作者:
[Wong WF, Tazawa R, (15名略)Nakata K, Takai T, Satake M.]
通讯作者:
Satake M.
Repertoire Analysis of GM-CSF Autoantibody mRNA by Next Generation Sequencing In Autoimmune Pulmonary Alveolar Proteinosis.
通过下一代测序对自身免疫性肺泡蛋白沉积症中的 GM-CSF 自身抗体 mRNA 进行全谱分析。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Nakata K, Nei T, Motoi N, Urano S, Tazawa R, Nakagaki K, Suzuki M, Takizawa J, Azuma A.]
通讯作者:
Azuma A.
DOI:
10.3389/fmicb.2014.00410
发表时间:
2014
期刊:
Frontiers in microbiology
影响因子:
5.2
作者:
[Saraya T, Kurai D, Nakagaki K, Sasaki Y, Niwa S, Tsukagoshi H, Nunokawa H, Ohkuma K, Tsujimoto N, Hirao S, Wada H, Ishii H, Nakata K, Kimura H, Kozawa K, Takizawa H, Goto H]
通讯作者:
Goto H
Prenatal molecular diagnosis of X-linked hydrocephalus via a silent C924T mutation in the L1CAM gene
通过 L1CAM 基因 C924T 沉默突变对 X 连锁脑积水进行产前分子诊断
DOI:
10.1111/cga.12069
发表时间:
2014
期刊:
Congenit Anom (Kyoto)
影响因子:
--
作者:
[Serikawa T, Nishiyama K, Tohyama J, Tazawa R, Goto K, Kuriyama Y, Haino K, Kanemura Y, Yamasaki M, Nakata K, Takakuwa K, Enomoto T.]
通讯作者:
Enomoto T.
共 7 条
Establishment and elucidation of a mathematical model that explains the pathogenesis of pulmonary alveolar proteinosis.
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批准号:15K15321
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2015
-
负责人:NAKATA Koh
-
依托单位:
Development of a novel disease severity marker for the inflammatory bowel diseases.
-
批准号:23659498
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2011
-
负责人:NAKATA Koh
-
依托单位:
A systematic research on immunomodulation in autoimmune pulumonary alveolar proteinpsis.
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批准号:20390230
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.31万
-
财政年份:2008
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负责人:NAKATA Koh
-
依托单位:
Why does the autoantibody against cytokine incease in patients with idiopathic pulmonary alveolar proteinosis?
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批准号:18390240
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.84万
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财政年份:2006
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负责人:NAKATA Koh
-
依托单位:
Roles of the autoantibody against GM-CSF in the pathogenesis, diagnosis, and treatment for idiopathic pulmonary alveolar proteinosis
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批准号:16390239
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.34万
-
财政年份:2004
-
负责人:NAKATA Koh
-
依托单位:
Etiology for idiopathic pulmonary alveolar proteinosis : Roles of the autoantibody against GM-CSF in the pathogenesis.
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批准号:13670624
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.5万
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财政年份:2001
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负责人:NAKATA Koh
-
依托单位:
海外基金