Integrative genomic and proteomic analyses of low-dose ionizing radiation in EBV infected-B cells

EBV 感染 B 细胞低剂量电离辐射的综合基因组和蛋白质组分析

• 批准号: 24501306
• 负责人: TABE Yoko
• 金额: $ 3.41万
• 依托单位: Juntendo University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24501306/
• 关键词: 低線量放射線; 微小環境; 前がん細胞; microRNA; プロテオミクス; miRNA; 骨髄微小環境; 間質細胞; アポトーシス

项目成果

Mechanisms of apoptosis induction by simultaneous inhibition of PI3K and FLT3-ITD in AML cells in the hypoxic bone marrow microenvironment.

• DOI: 10.1016/j.canlet.2012.09.020
• 发表时间: 2013-02-01
• 期刊: CANCER LETTERS
• 影响因子: 9.7
• 作者: Jin, Linhua;Tabe, Yoko;Lu, Hongbo;Borthakur, Gautam;Miida, Takashi;Kantarjian, Hagop;Andreeff, Michael;Konopleva, Marina
• 通讯作者: Konopleva, Marina

Performance evaluation of a novel high-risk Human Papilloma Virus Genotyping test (Clinichip HPV™).

新型高风险人乳头瘤病毒基因分型测试 (Clinichip HPV™) 的性能评估。

• 发表时间: 2013
• 作者: Yamada H;Tabe Y;Ishii K;Terao Y;Takeda S;Horii T;Ohsaka A.
• 通讯作者: Ohsaka A.

Molecular Mechanisms of Pro-Survival and Differentiating Function of Bone Marrow-Derived Adipocytes On Acute Monoblastic Leukemia Cells.

骨髓源性脂肪细胞对急性单核细胞白血病细胞的促生存和分化功能的分子机制。

• 发表时间: 2012
• 作者: Linhua Jin;Marina Konopleva;Masato Shikami;Takako Ikegami;Kensuke Kojima ;MichaellAndreeff;Takashi Miida;Yoko Tabe
• 通讯作者: Yoko Tabe

Bone marrow adipocyte-derived free fatty acids induce gene signature linking transcription with metabolic changes that contribute to survival of acute monocytic leukemia cells

骨髓脂肪细胞衍生的游离脂肪酸诱导基因特征，将转录与有助于急性单核细胞白血病细胞存活的代谢变化联系起来

• 发表时间: 2014
• 作者: Yoko Tabe;Masako Harada;Yuka Miyamae;Kaoru Mogushi;Saiko Kazuno;Tsutomu Fujimura;Hiromichi Matsushita;Takashi Ueno;Takehiko Yokomizo;Takashi Miida;Ismael Samudio;Michael Andreeff;Marina Konopleva.
• 通讯作者: Marina Konopleva.

WBC differentiation Procedures

白细胞分化程序

• 发表时间: 2012
• 作者: Yoko Tabe;Naotake Satoh;Chiaki Tanaka
• 通讯作者: Chiaki Tanaka