New Therapy for Intractable Pulmonary Fibrosis using Humoral Factors released from Mesenchymal Stem Cells
New Therapy for Intractable Pulmonary Fibrosis using Humoral Factors released from Mesenchymal Stem Cells
批准号:
24591149
负责人:
OHKOUCHI Shinya
金额:
$3.49万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2015-03-31
中文摘要
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英文摘要
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The enhancement of Stanniocalcin-1 (STC1) secretion increases the ability of mesenchymal stem cells (MSCs) to reduce bleomycin-induced lung fibrosis in a mouse model through inhibition of endoplasmic reticulum stress (ER-stress)/TGFbeta1 pathway
在小鼠模型中,斯钙素-1 (STC1) 分泌的增强可增加间充质干细胞 (MSC) 通过抑制内质网应激 (ER-stress)/TGFbeta1 途径减少博莱霉素诱导的肺纤维化的能力
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Shinya Ohkouchi, Manabu Ono and Masakazu Ichinose]
通讯作者:
Manabu Ono and Masakazu Ichinose
治療薬Up-to-Date
治疗药物最新
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[共同執筆, 監修・矢崎義雄, 大河内眞也]
通讯作者:
大河内眞也
The enhancement of Stannniocalcin-1 (STC1) secretion of Multipotent-Stromal-Cells (MSCs) increases the ability to reduce bleomycin-induced lung injuries.
多能基质细胞 (MSC) 的斯钙素-1 (STC1) 分泌增强,可增加减少博来霉素引起的肺损伤的能力。
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Manabu Ono*, Shinya Ohkouchi, Masahiko Kanehira, Naoki Tode, Makoto Kobayashi, Tadahisa Numakura, Toshiaki Kikuchi and Masakazu Ichinose.]
通讯作者:
Toshiaki Kikuchi and Masakazu Ichinose.
PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATING FIBROSIS
用于预防或治疗纤维化的药物组合物
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[]
通讯作者:
The Enhancement Of Stanniocalcin-1 (STC1) Secretion Increases The Ability Of Mesenchymal Stem Cells (MSCs) Reducing Bleomycin-Induced Lung Fibrosis In Mice Model Through Inhibition Of ROS/Endoplasmic Reticulum Stress (ER-Stress)/TGFβ1 Pathway
斯钙素-1 (STC1) 分泌的增强增强间充质干细胞 (MSC) 通过抑制 ROS/内质网应激 (ER-应激)/TGFβ1 途径减少博来霉素诱导的小鼠肺纤维化的能力
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[M. Ono, graduate student, S. Ohkouchi, M.D. PhD., M. Kanehira, PhD, N. Tode, MD, T. Kikuchi, MD, PhD, M. Ichinose, Prof]
通讯作者:
Prof
共 11 条
Identification of paracrine factors from mesenchaymal stem cell for protection and treatment against lung injury
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批准号:21590980
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2009
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负责人:OHKOUCHI Shinya
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依托单位:
海外基金