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Fundamental research on the material development of high biocompatibility applying tannic acid

Fundamental research on the material development of high biocompatibility applying tannic acid
应用单宁酸的高生物相容性材料开发基础研究
批准号:
24792128
负责人:
NAKAMURA Koichi
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31

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中文摘要
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英文摘要
Glass ionomer cement have a fluoride-releasing.It is said that pulp affinity is high. At first, We examined for the presence of cytotoxic.It was found that COX-2 mRNA expression was induced by cement elution.Tannic acid suppressed the phenomenon. The increased expression of COX-2 mRNA and protein and the production of PGE2 by cement elution. Furthermore, activation of intracellular signal transduction systems present in the upstream was observed. Tannic acid was found to suppress them.
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