Research on efficient compilation and promotion of disease knowledge base

疾病知识库高效构建与推广研究

• 批准号: 24680027
• 负责人: OKUMURA Takashi
• 金额: $ 11.65万
• 依托单位: National Institute of Public Health
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (A)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24680027/
• 关键词: 医療情報; 疾患知識ベース; 診断支援システム

Improvement of information systems for clinical practices requires a disease knowledge base that contains possible clinical findings and laboratory examination results for each disease. However, compilation of such knowledge base necessitates considerable time and money. Accordingly, this study proposed to hybridize the data for major diseases, manually compiled to guarantee necessary quality, and the data for rare diseases, automatically generated for broader coverage, in the aim of efficient compilation of practical disease knowledge base. Additionally, toward quality control of the resulting knowledge base, a diagnostic decision support system is built with a feedback mechanism to collect usage information to efficiently improve the quality of the disease knowledge base. The research yielded disease knowledge base and a diagnostic decision support system with practical quality, as well as various knowledge about automatic acquisition of disease knowledge out of medical literature.

改善临床实践的信息系统需要一个疾病知识库，其中包含每种疾病可能的临床结果和实验室检查结果。然而，编制这样的知识库需要相当多的时间和金钱。因此，本研究建议将人工编制的重大疾病数据与自动生成的罕见病数据进行混合，以确保必要的质量，以便覆盖更广的范围，以期高效地编制实用的疾病知识库。此外，针对知识库的质量控制，建立了一个具有反馈机制的诊断决策支持系统，以收集使用信息，从而有效地提高疾病知识库的质量。该研究产生了具有实用质量的疾病知识库和诊断决策支持系统，以及从医学文献中自动获取疾病知识的各种知识。

项目成果

疾患知識ベースのcommunity-driven currationと診断支援プラットフォーム

社区驱动的疾病知识库和诊断支持平台的管理

• 发表时间: 2013
• 作者: M. Shimizu;S. Yawata;K. Miyasaka;K. Miyamoto;T. Asano;T. Yoshinobu;H. Yawo;T. Ogura;and A. Ishiguro;奥村貴史,荒牧英治,建石由佳
• 通讯作者: 奥村貴史,荒牧英治,建石由佳

A lightweight approach for extracting disease-symptom relation with Meta〓toward automated generation of disease knowledge base

一种利用Meta〓自动生成疾病知识库来提取疾病症状关系的轻量级方法

• DOI: 10.1007/978-3-642-29361-0_20
• 发表时间: 2012
• 期刊: 1st International Conference on Health Information Science(HIS2012)
• 作者: Shuang Wu;Junpei Kawamoto;Hiroaki Kikuchi;Jun Sakuma;清水正宏，民山浩輔，宮坂恒太，宮坂恒太，中井淳一，大倉正道，細田耕;森裕紀;T. Okumura and Y. Tateishi
• 通讯作者: T. Okumura and Y. Tateishi

A lightweight approach for extracting disease-symptom relation with MetaMap toward automated generation of disease knowledge base

一种利用 MetaMap 提取疾病症状关系以自动生成疾病知识库的轻量级方法

• 发表时间: 2012
• 作者: T. Okumura;and Y. Tateishi
• 通讯作者: and Y. Tateishi

A Simple Approach to NTCIR-10 MedNLP task

NTCIR-10 MedNLP 任务的简单方法

• 发表时间: 2013
• 期刊: 10th NII Testbeds and Community for Information access Research
• 作者: 長谷川 聡;佐久間 淳;T. Okumura and Y. Tateishi
• 通讯作者: T. Okumura and Y. Tateishi

Hierarchical representation of differential diagnosis lists for clinical decision support systems

临床决策支持系统鉴别诊断列表的分层表示

• 发表时间: 2014
• 作者: Shuang Wu,Tadanori Teruya;Junpei Kawamoto;Jun Sakuma;Hiroaki Kikuchi;熊倉翔平;T. Okumura and M. Tagawa
• 通讯作者: T. Okumura and M. Tagawa