Correlation study of the uncinate fasciculus and memory function of healthy individuals using diffusion tensor tractography

扩散张量纤维束成像技术对健康人钩束与记忆功能的相关性研究

• 批准号: 24700456
• 负责人: SATO Tetsuo
• 金额: $ 2.41万
• 依托单位: Nara Institute of Science and Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24700456/
• 关键词: 医用・生体画像; 拡散テンソルMRI

Tractography is a procedure that can track and demonstrate the 3D neural tracts of the white matter of the brain. Studying these connections is integral to the understanding of the brain function. Specifically, the uncinate fasciculus (UF), which is the white matter in the human brain, is said to be related to cognitive function. The UF tractography is calculated using diffusion tensor imaging (DTI) parameter. Studies have shown that the DTI parameter of dementia patients is lower than that of healthy individuals. It is also suggested that the DTI parameter of healthy individuals decreases with age. In addition, the WMS-R score, which is indicative of general memory, verbal memory and other cognitive functions, of the elderly are lower than of the young. Thus, in this research, we have investigated the correlation between the DTI parameter of UF and WMS-R score.

神经束造影是一种可以追踪和显示大脑白质的三维神经束的方法。研究这些联系对于理解大脑功能是不可或缺的。具体来说，钩状束（UF），即人类大脑中的白质，据说与认知功能有关。利用扩散张量成像（diffusion tensor imaging， DTI）参数计算超滤示踪。研究表明，痴呆患者的DTI参数低于健康人。健康个体的DTI参数随年龄的增长而降低。此外，老年人的一般记忆、言语记忆等认知功能的WMS-R评分低于年轻人。因此，在本研究中，我们研究了UF的DTI参数与WMS-R评分之间的相关性。

项目成果

Comparison of Relationships between Two Different White Matter Tracts and Memory Function with Healthy Individuals by Using Diffusion Tensor Tractography

利用扩散张量束成像技术比较两种不同白质束与健康个体记忆功能的关系

• 发表时间: 2014
• 作者: Tetsuo Sato;Nobuyuki Maruyama;Toru Hoshida;Kotaro Minato
• 通讯作者: Kotaro Minato

Correlation between uncinate fasciculus and memory tasks in healthy individual using diffusion tensor tractography

• DOI: 10.1109/embc.2012.6345958
• 发表时间: 2012-11
• 期刊: 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society
• 作者: Tetsuo Sato;N. Maruyama;T. Hoshida;K. Minato

記憶機能における前頭側頭神経束とMRスペクトロスコピーの相関

额颞神经束与磁共振波谱在记忆功能中的相关性

• 发表时间: 2013
• 作者: Tetsuo Sato;Nobuyuki Maruyama;Tohru Hoshida;Kotaro Minato;密山京太,佐藤哲大,星田徹,丸山信之,湊小太郎
• 通讯作者: 密山京太,佐藤哲大,星田徹,丸山信之,湊小太郎

Effects comparison of DTI registrations by two different input images on whole brain tractography

两种不同输入图像的 DTI 配准对全脑纤维束成像的效果比较

• 发表时间: 2012
• 作者: Ohira H;Fujioka Y;Katagiri C;Mamoto R;Aoyama M;Izumi Y;Nishiumi S;Yoshida M;Usami M;Ikeda M.;Tetsuo Sato and Kotaro Minato
• 通讯作者: Tetsuo Sato and Kotaro Minato

Correlation between Diffusion Tensor Tractography and proton MR spectroscopy in normal controls

正常对照中扩散张量纤维束成像与质子磁共振波谱之间的相关性

• 发表时间: 2014
• 作者: Tetsuo Sato;Nobuyuki Maruyama;Toru Hoshida;Kotaro Minato
• 通讯作者: Kotaro Minato