Correlation study of the uncinate fasciculus and memory function of healthy individuals using diffusion tensor tractography

神经束造影是一种可以追踪和显示大脑白质的三维神经束的方法。研究这些联系对于理解大脑功能是不可或缺的。具体来说，钩状束（UF），即人类大脑中的白质，据说与认知功能有关。利用扩散张量成像（diffusion tensor imaging， DTI）参数计算超滤示踪。研究表明，痴呆患者的DTI参数低于健康人。健康个体的DTI参数随年龄的增长而降低。此外，老年人的一般记忆、言语记忆等认知功能的WMS-R评分低于年轻人。因此，在本研究中，我们研究了UF的DTI参数与WMS-R评分之间的相关性。

Tractography is a procedure that can track and demonstrate the 3D neural tracts of the white matter of the brain. Studying these connections is integral to the understanding of the brain function. Specifically, the uncinate fasciculus (UF), which is the white matter in the human brain, is said to be related to cognitive function. The UF tractography is calculated using diffusion tensor imaging (DTI) parameter. Studies have shown that the DTI parameter of dementia patients is lower than that of healthy individuals. It is also suggested that the DTI parameter of healthy individuals decreases with age. In addition, the WMS-R score, which is indicative of general memory, verbal memory and other cognitive functions, of the elderly are lower than of the young. Thus, in this research, we have investigated the correlation between the DTI parameter of UF and WMS-R score.