Possibility of the whole body supply of hydrogen formed in large intestine and the nutritional role

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The aim of this study is to clarify that a part of hydrogen derived from large intestine moved to the organs of the whole body and supplied hydrogen contributed to reduce the oxidation stress of whole bodies such as the obesity.At first we analyzed biodistribution of hydrogen derived from large intestine and found that hydrogen concentration in portal blood, liver, perirenal fat, epididimal fat rose. In addition, we proposed that it could not supply hydrogen to all organs only by the course through the portal vein.We examined the influence that a genetic background to cause the obesity of the hereditary obesity model mouse gave for hydrogen and hydrogen large intestine generation due to fructan was stronger than a wild type mouse and clarified that it was guided.