The strategy for treatment based on the association cascade with the amyotrophic lateral sclerosis causative genes and RNA editing enzyme
The strategy for treatment based on the association cascade with the amyotrophic lateral sclerosis causative genes and RNA editing enzyme
批准号:
25461266
负责人:
TAKUMA Hiroshi
金额:
$3.24万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2013
资助国家:
日本
项目状态:
已结题
起止时间:
2013-04-01 至 2016-03-31
中文摘要
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DOI:
10.1093/hmg/ddt451
发表时间:
2014-02-01
期刊:
HUMAN MOLECULAR GENETICS
影响因子:
3.5
作者:
[Iwata, Atsushi, Nagata, Kenichi, Tsuji, Shoji]
通讯作者:
Tsuji, Shoji
ブレインサイエンス・レビュー 2014 筋萎縮性側索硬化症治療に向けた新規モデル開発とRNA関連因子
脑科学评论 2014 肌萎缩侧索硬化症治疗的新模型开发和 RNA 相关因素
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[A. IWATA, K. NAGATA, H. HATSUTA, H. TAKUMA, M. BUNDO, K. IWAMOTO, A. TAMAOKA, S. MURAYAMA, T. C. SAIDO, S. TSUJI, 詫間 浩]
通讯作者:
詫間 浩
TDP-43 aggregation produced by In utero electroporation and its properties in the mouse motor neurons.
子宫内电穿孔产生的 TDP-43 聚集及其在小鼠运动神经元中的特性。
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[9.Akamatsu M, Takuma H, Yamashita T, Okada T, Ishii K, Keino-Masu K, Kwak S, Masu M, Tamaoka A]
通讯作者:
Tamaoka A
子宮内電気穿孔法TDP-43 遺伝子導入によるin vivo形成封入体の微細形態の検討
宫内电穿孔 TDP-43 基因转移体内形成的包涵体微形态检查
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[詫間浩、赤松恵、山下雄也、Oehring, H.、岡田拓也、桝和子、石井一弘、Jirikowski, G、郭伸、桝正幸、玉岡晃]
通讯作者:
G、郭伸、桝正幸、玉岡晃
Neurodegenerative disorder FTDP-17-related tau intron 10 +16C → T mutation increases tau exon 10 splicing and causes tauopathy in transgenic mice.
神经退行性疾病 FTDP-17 相关 tau 内含子 10 +16C → T 突变会增加 tau 外显子 10 剪接并导致转基因小鼠中的 tau 病。
DOI:
10.1016/j.ajpath.2013.03.015
发表时间:
2013
期刊:
Am J Pathol.
影响因子:
--
作者:
[Umeda T, Yamashita T, Kimura T, Ohnishi K, Takuma H, Ozeki T, Takashima A, Tomiyama T, Mori H.]
通讯作者:
Mori H.
共 10 条
The therapeutic strategy for amyotrophic lateral sclerosis by elucidation and removal of accumulated protein-cleaving factors
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批准号:16K09681
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2016
-
负责人:TAKUMA Hiroshi
-
依托单位:
Involvement of RNA-editing enzyme and multi-factor to motor neuron death in patients with sporadic amyotrophic lateral sclerosis
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批准号:21591071
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2009
-
负责人:TAKUMA Hiroshi
-
依托单位:
Screening for new substrate and development of bio-marker for RNA editing enzyme in sporadic amyotrophic lateral sclerosis
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批准号:19599003
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.21万
-
财政年份:2007
-
负责人:TAKUMA Hiroshi
-
依托单位:
Alternated splicing of tau in development and neurodegenerating disorders with dementia.
-
批准号:16590841
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.92万
-
财政年份:2004
-
负责人:TAKUMA Hiroshi
-
依托单位:
A study for the contribution of RNA editing abnormality in sporadic Alzheimer's disease.
-
批准号:13670662
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2001
-
负责人:TAKUMA Hiroshi
-
依托单位:
Time Budget Survey of University Researchers
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批准号:06306009
-
项目类别:Grant-in-Aid for Co-operative Research (A)
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资助金额:$0.0万
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财政年份:1994
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负责人:TAKUMA Hiroshi
-
依托单位:
INVESTIGATION OF ATOM IMAGING BY ELECTRIC FIELD
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批准号:04402010
-
项目类别:Grant-in-Aid for General Scientific Research (A)
-
资助金额:$11.01万
-
财政年份:1992
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负责人:TAKUMA Hiroshi
-
依托单位:
EXCIMER FORMATION AND RELUXATION STUDIED BY CROSSED MOLECULAR BEAM EXPERIMENT
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批准号:62460038
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.35万
-
财政年份:1987
-
负责人:TAKUMA Hiroshi
-
依托单位:
Study on Ultra-high Frequency-Stabilization Techniques of Tunable Dye Lasers
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批准号:63043024
-
项目类别:Grant-in-Aid for Overseas Scientific Research
-
资助金额:$0.58万
-
财政年份:1987
-
负责人:TAKUMA Hiroshi
-
依托单位:
海外基金