心血管疾患リスクおよび死亡率の関連因子としての精神ストレス

精神压力是与心血管疾病风险和死亡率相关的一个因素

• 批准号: 15J05980
• 负责人: SVENSSON THOMAS
• 金额: $ 1.22万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for JSPS Fellows
• 财政年份: 2015
• 资助国家: 日本
• 起止时间: 2015-04-24 至 2017-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15J05980/
• 关键词: Coping; Stress; Cardiovascular disease; Cancer; Epidemiology; Cohort; Incidence; Mortality

My research over the past two years has progressed in accordance with the initial timeline defined in my grant application.The first goal was to investigate the association between stress coping strategies and disease. This has been accomplished and resulted in two publications of which one was considered Editors’Choice. The results of the second article were highlighted by NHK News.The second goal was to investigate if genetic susceptibility to coronary heart disease modified the effect of stress on cardiovascular disease. The results of this study were presented at the prestigious ESC Congress in Rome, and the manuscript has been accepted for publication in PLOS ONE.I have also managed additional publications outside the current grant proposal (for details, please see below).

在过去的两年里，我的研究一直在按照我的资助申请中确定的初步时间表进行。第一个目标是调查压力应对策略和疾病之间的关系。这项工作已经完成，并产生了两份出版物，其中一份被认为是编辑之选。NHK新闻重点报道了第二篇文章的结果。第二个目标是调查冠心病的遗传易感性是否改变了应激对心血管疾病的影响。这项研究的结果在罗马著名的ESC大会上发表，手稿已被接受发表在PLOS ONE上。我还管理了当前资助提案之外的其他出版物（详细信息请参见下文）。

项目成果

がんセンター リサーチニュース

癌症中心研究新闻

The association between complete and partial non-response to psychosocial questions and suicide: the JPHC Study

• DOI: 10.1093/eurpub/cku209
• 发表时间: 2015-06-01
• 期刊: EUROPEAN JOURNAL OF PUBLIC HEALTH
• 影响因子: 4.4
• 作者: Svensson, Thomas;Inoue, Manami;Tsugane, Shoichiro
• 通讯作者: Tsugane, Shoichiro

Coping strategies and risk of cardiovascular disease incidence and mortality: the Japan Public Health Center-based prospective Study

• DOI: 10.1093/eurheartj/ehv724
• 发表时间: 2016-03-14
• 期刊: EUROPEAN HEART JOURNAL
• 影响因子: 39.3
• 作者: Svensson, Thomas;Inoue, Manami;Tsugane, Shoichiro
• 通讯作者: Tsugane, Shoichiro

Lund University(Sweden)

隆德大学（瑞典）

Genetic Risk Score, individual genetic variants and psychological stress as predictors of CAD, fatal MI and cardiovascular death

遗传风险评分、个体遗传变异和心理压力作为 CAD、致命性心肌梗死和心血管死亡的预测因素

• 发表时间: 2016
• 作者: Hiraoka T;Hirota Y;Saito-Fujita T;Matsuo M;Egashira M;Matsumoto L;Haraguchi H;Dey SK;Furukawa KS;Fujii T;Osuga Y.;Thomas Svensson
• 通讯作者: Thomas Svensson