Related elucidation of the tissue-specific pudding metabolism state and lifestyle-related disease

组织特异性布丁代谢状态与生活方式相关疾病的相关阐明

• 批准号: 16K09791
• 负责人: Kushiyama Akifumi
• 金额: $ 3万
• 依托单位: The Institute for Adult Diseases Asahi Life Foundation
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K09791/
• 关键词: 尿酸代謝; 核酸代謝; 生活習慣病; キサンチンオキシダーゼ; プリン体代謝異常

项目成果

The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice.

• DOI: 10.3390/ijms18081704
• 发表时间: 2017-08-04
• 期刊: International journal of molecular sciences
• 影响因子: 5.6
• 作者: Nakatsu Y;Kokubo H;Bumdelger B;Yoshizumi M;Yamamotoya T;Matsunaga Y;Ueda K;Inoue Y;Inoue MK;Fujishiro M;Kushiyama A;Ono H;Sakoda H;Asano T
• 通讯作者: Asano T

C-Peptide Level in Fasting Plasma and Pooled Urine Predicts HbA1c after Hospitalization in Patients with Type 2 Diabetes Mellitus.

• DOI: 10.1371/journal.pone.0147303
• 发表时间: 2016
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Sonoda R;Tanaka K;Kikuchi T;Onishi Y;Takao T;Tahara T;Yoshida Y;Suzawa N;Kawazu S;Iwamoto Y;Kushiyama A
• 通讯作者: Kushiyama A

Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.

• DOI: 10.1155/2016/8603164
• 发表时间: 2016
• 期刊: Mediators of inflammation
• 影响因子: 4.6
• 作者: Kushiyama A;Nakatsu Y;Matsunaga Y;Yamamotoya T;Mori K;Ueda K;Inoue Y;Sakoda H;Fujishiro M;Ono H;Asano T
• 通讯作者: Asano T

Alpha-Blockers As Colorectal Cancer Chemopreventive: Findings from a Case?Control Study, Human Cell Cultures, and In Vivo Preclinical Testing

α-受体阻滞剂作为结直肠癌的化学预防：病例对照研究、人类细胞培养和体内临床前测试的结果

• DOI: 10.1158/1940-6207.capr-18-0288
• 发表时间: 2019
• 期刊: Cancer Prevention Research
• 影响因子: 3.3
• 作者: Suzuki Nobumi;Niikura Ryota;Ihara Sozaburo;Hikiba Yohko;Kinoshita Hiroto;Higashishima Naoko;Hayakawa Yoku;Yamada Atsuo;Hirata Yoshihiro;Nakata Ryo;Okamoto Makoto;Sano Munetaka;Kushiyama Akifumi;Ichinose Mari;Woods Susan L.;Worthley Daniel;Iwamoto Yasuhiko
• 通讯作者: Iwamoto Yasuhiko

Serum uric acid is an independent predictor of new-onset diabetes after living-donor kidney transplantation

• DOI: 10.1186/s41100-018-0169-4
• 发表时间: 2018-07
• 期刊: Renal Replacement Therapy
• 影响因子: 1.2
• 作者: Kentaro Tanaka;K. Sakai;A. Kushiyama;S. Hara;Masakazu Hattori;Y. Ohashi;M. Muramatsu;T. Kawamura;S. Shishido;A. Aikawa