Carcinogenic mechanisms of stem cells in inflammation-related cancer and its prevention

干细胞在炎症相关癌症中的致癌机制及其预防

• 批准号: 16H05255
• 负责人: Murata Mariko
• 金额: $ 10.65万
• 依托单位: Mie University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16H05255/
• 关键词: がん; 炎症; 幹細胞; 8-ニトログアニン; エピゲノム異常; CD44v9; HMGB1; 炎症関連発がん; DNA損傷; 癌; 遺伝子損傷

项目成果

Prolonged oxidative stress down-regulates Early B cell factor 1 with inhibition of its tumor suppressive function against cholangiocarcinoma genesis.

• DOI: 10.1016/j.redox.2017.11.011
• 发表时间: 2018-04
• 期刊: Redox biology
• 影响因子: 11.4
• 作者: Armartmuntree N;Murata M;Techasen A;Yongvanit P;Loilome W;Namwat N;Pairojkul C;Sakonsinsiri C;Pinlaor S;Thanan R
• 通讯作者: Thanan R

Multi-walled carbon nanotube induces nitrative DNA damage in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation.

• DOI: 10.1186/s12989-016-0127-7
• 发表时间: 2016-03-29
• 期刊: Particle and fibre toxicology
• 影响因子: 10
• 作者: Hiraku Y;Guo F;Ma N;Yamada T;Wang S;Kawanishi S;Murata M
• 通讯作者: Murata M

Glutaredoxin 3 promotes nasopharyngeal carcinoma growth and metastasis via EGFR/Akt pathway and independent of ROS.

• DOI: 10.18632/oncotarget.9454
• 发表时间: 2016-06-14
• 期刊: Oncotarget
• 作者: He F;Wei L;Luo W;Liao Z;Li B;Zhou X;Xiao X;You J;Chen Y;Zheng S;Li P;Murata M;Huang G;Zhang Z
• 通讯作者: Zhang Z

Khon Kean University(タイ)

孔敬大学（泰国）

Nitrative DNA damage in lung epithelial cells exposed to particulate and soluble indium compounds

暴露于颗粒和可溶性铟化合物的肺上皮细胞的硝基 DNA 损伤

• 发表时间: 2019
• 作者: Sharif Ahmed;Tahmina Afroz;馬寧、川西正祐、村田真理子、平工雄介
• 通讯作者: 馬寧、川西正祐、村田真理子、平工雄介