Investigation of the effect of the tissue microenvironment on tumor cells through TRPV4 channel

通过TRPV4通道研究组织微环境对肿瘤细胞的影响

• 批准号: 16K11738
• 负责人: Ozeki Satoru
• 金额: $ 3.08万
• 依托单位: National Hospital Organization, Kyushu Medical Center (Clinical Institute)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K11738/
• 关键词: 癌; TRPチャネル; Hippoシグナル; 口腔がん; 扁平上皮がん; がん

项目成果

Facioscapulohumeral muscular dystrophy (FSHD) region gene 1 (FRG1) expression and possible function in mouse tooth germ development

• DOI: 10.1007/s10735-016-9680-5
• 发表时间: 2016-08-01
• 期刊: JOURNAL OF MOLECULAR HISTOLOGY
• 影响因子: 3.2
• 作者: Hasegawa, Kana;Wada, Hiroko;Kiyoshima, Tamotsu
• 通讯作者: Kiyoshima, Tamotsu

GLI-mediated Keratin 17 expression promotes tumor cell growth through the anti-apoptotic function in oral squamous cell carcinomas

• DOI: 10.1007/s00432-017-2398-2
• 发表时间: 2017-03
• 期刊: Journal of Cancer Research and Clinical Oncology
• 影响因子: 3.6
• 作者: Y. Mikami;S. Fujii;K. Nagata;H. Wada;Kana Hasegawa;Misaki Abe;Reiko U. Yoshimoto;S. Kawano

Clinicopathological evaluation of preoperative chemoradiotherapy with S-1 for locally advanced oral squamous cell carcinoma.

S-1术前放化疗治疗局部晚期口腔鳞状细胞癌的临床病理学评价。

• 发表时间: 2016
• 期刊: Oncol Lett.
• 作者: Shintaro Kawano;Yanqun Zheng;Kazunari Oobu;Ryota Matsubara;Yuichi Goto;Toru Chikui;Tadamasa Yoshitake;Tamotsu Kiyoshima;Teppei Jinno;Yasuyuki Maruse;Eiji Mitate;Ryoji Kitamura;Hideaki Tanaka;Takeshi Toyoshima;Tsuyoshi Sugiura;Seiji Nakamura
• 通讯作者: Seiji Nakamura

ヒト口腔癌におけるTRPV4の発現と機能解析

TRPV4在人口腔癌中的表达及功能分析

• 发表时间: 2018
• 作者: 田尻祐大;藤井慎介;大関悟;清島保
• 通讯作者: 清島保

A case of adenosquamous carcinoma observed in the metastatic lymph node, but not in the primary lesion.

一例在转移性淋巴结中观察到腺鳞癌，但在原发灶中未观察到的腺鳞癌。

• 发表时间: 2016
• 作者: Yurie Mikami;Hiroko Wada;Kazunari Oobu;Seiji Nakamura;Tamotsu Kiyoshima
• 通讯作者: Tamotsu Kiyoshima