Molecular and structural characterization of photoreceptor cells in Lophotrochozoa in order to utilise the photosensitive system as comparative character for inferring metazoan interrelationships. II. Eyes and photoreceptors of Mollusca and Platyhelminthe

轮轮动物感光细胞的分子和结构表征，以便利用光敏系统作为推断后生动物相互关系的比较特征。

• 批准号: 5452242
• 负责人: Professor Dr. Detlev Arendt
• 金额: --
• 依托单位: Europäisches Laboratorium für Molekularbiologie (EMBL)
• 依托单位国家: 德国
• 项目类别: Priority Programmes
• 财政年份: 2005
• 资助国家: 德国
• 起止时间: 2004-12-31 至 2014-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/5452242?language=en
• 关键词: Molecular; structural; characterization; photoreceptor; cells

Our project aims at the combined molecular and morphological characterisation of photophotoreceptor cells and eyes in molluscs, nemerteans, brachiopods and flatworms, to compare these to each other and to photosensitive systems in annelids. We will thus identify and explore useful characters for resolving the phylogeny of the Lophotrochozoa, which is a large and illdefined taxon of marine invertebrate animal groups. We plan to investigate opsin photopigment, shading pigment, specifying transcription factors as well as the ultrastructure of photoreceptor, pigment and support cells that constitute the diverse light-sensitive organs (ocelli, eyes and unpigmented organs). Selected species include gastropods, polyplacophorans representing molluscs, triclades and proseriates representing flatworms, palaeonemerteans and heteronemerteans representing nemerteans, and a brachiopod species, to complement our previous studies. We will focus on the identification of orthologous and paralogous opsin photopigment in the various groups, and how the distinct subfamilies of opsins distribute to the different types of photoreceptor cells, such as cililary and rhabdomeric photoreceptors. This will allow identifying lines of photoreceptor and eye evolution across lophotrochozoan phylogeny.

我们的项目旨在结合分子和形态学特征的光感受器细胞和眼睛的软体动物，纽形动物，腕足动物和扁形虫，比较这些彼此之间和环节动物的光敏系统。因此，我们将确定和探索有用的字符解决的Lophotrochozoa，这是一个大型的和不明确的分类海洋无脊椎动物群的繁殖。我们计划研究视蛋白色素，着色色素，指定转录因子以及感光细胞，色素和支持细胞的超微结构，构成不同的光敏感器官（单眼，眼睛和无色素器官）。所选物种包括腹足类，polyplacophorans代表软体动物，triclades和proseriates代表扁形虫，palaeonemerteans和heteronemerteans代表纽形动物，和腕足类物种，以补充我们以前的研究。我们将集中在识别的orthopathic和paralogous视蛋白色素在不同的群体，以及不同的亚家族的视蛋白分布到不同类型的感光细胞，如纤毛和横纹肌感光细胞。这将使识别线的感光细胞和眼睛的进化跨越lophotrochozoan spermogeny。