Molecular Morphology of the Metazoa, with Special Reference to the Lophotrochozoa (MOLMORPH)

后生动物的分子形态学，特别是冠轮动物 (MOLMORPH)

• 批准号: 5452298
• 负责人: Professor Dr. Gerhard Haszprunar
• 金额: --
• 依托单位: Zoologische Staatssammlung München
• 依托单位国家: 德国
• 项目类别: Priority Programmes
• 财政年份: 2005
• 资助国家: 德国
• 起止时间: 2004-12-31 至 2009-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/5452298?language=en
• 关键词: Molecular; Morphology; Metazoa; Special; Reference

Within the New Animal Phylogeny the concept of Lophotrochozoa (i.e. inclusion of Lophophorata = Tentaculata and Spiralia in one clade to the exclusion of Arthropoda) is still one of the heavily debated points. Up to now molecular data have failed to infer the interrelationship of lophotrochozoan phyla, and available morphological data are not conclusive. The highly innovative type of analysis called molecular morphology (i.e., the morphological analysis of 2D- or 3D-structure of the studied molecules) should provide new and valuable data fields. - The 2D-/3D-structures of genes usually applied for deep phylogeny (18 S and 28S rDNA, EF1a; HSP70, Myosin II) are known to be much more conservative than the primary structure (the linear sequence). In particular InDels (insertions or deletions) become highly significant characters in the 2D-/3D-image. Focusing on the lophotrochozoan taxa, where a large number of well-accepted clades exist, the molecular-morphological data-set will be tested and will add new characters to be considered. The type a can be directly added to a morphological data-matrix and will probably also improve the quality of the sequence analysis in order to provide better insights for evolutionary modelling of sequence substitution models.

在新动物系统发育中，Lophotrochozoa的概念（即将Lophophorata = Tentaculata和Spiralia包含在一个分支中，而将Arthropoda排除在外）仍然是一个备受争议的问题。到目前为止，分子数据未能推断出lophotrochozoan门的相互关系，可用的形态学数据也不是结论性的。高度创新的分析类型称为分子形态学（即，所研究分子的2D或3D结构的形态学分析）应该提供新的和有价值的数据领域。- 已知通常用于深层胚胎发生的基因的2D/3D结构（18 S和28 S rDNA，EF 1a; HSP 70，肌球蛋白II）比一级结构（线性序列）保守得多。特别地，InDel（插入或删除）在2D/3D图像中成为高度显著的字符。集中在lophotrochozoan类群，其中存在大量公认的分支，分子形态学数据集将进行测试，并将添加新的字符被考虑。类型a可以直接添加到形态学数据矩阵中，并且还可能提高序列分析的质量，以便为序列替代模型的进化建模提供更好的见解。