Using Cerebral Characters to Reconstruct Deep Metazoan Phylogeny: Comparative neuroarchitecture of the brain in annelids, molluscs and arthropods analyzed with confocal laser scanning microscopy

利用大脑特征重建深层后生动物系统发育：用共焦激光扫描显微镜分析环节动物、软体动物和节肢动物大脑的比较神经结构

• 批准号: 5452335
• 负责人: Privatdozent Dr. Rudolf Lösel
• 金额: --
• 依托单位: Geschäftsbereich Biologische Innovation und Ökonomie (BIO) (aufgelöst)
• 依托单位国家: 德国
• 项目类别: Priority Programmes
• 财政年份: 2005
• 资助国家: 德国
• 起止时间: 2004-12-31 至 2011-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/5452335?language=en
• 关键词: Using; Cerebral; Characters; Reconstruct; Deep

Numerous anatomical features of the brain of arthropods are highly conserved during evolution, including the presence and basic neuroarchitecture of neuropils such as the central body and the mushroom bodies. These features are therefore ideal markers from which to derive phylogenetic relationships of arthropods with other major groups of the animal kingdom. While the literature on euarthropod brain architecture is abundant there have been only sparse and superficial reports examining the internal structure of cerebral ganglia of most other invertebrate phyla. In the beginning of “Deep Metazoan Phylogeny” we have analyzed in detail the neuroarchitecture of basal representatives of euarthopods and of onychophorans, resulting in a clearer picture of the ground pattern of the brain of panarthropods. We have investigated the cellular anatomy of several representatives of the Annelida, and during the second application period, of the Mollusca. The aim of the project is to compare the ground pattern of the arthropod brain to that of annelids and molluscs. The analysis of the annelid brain is in an advanced stage and will be supplemented by detailed investigations of brain centers of special interest. We will continue to investigate cerebral ganglia of basal molluscs, a group that is otherwise not covered by morphological projects within DMP. The use of immunofluorescence antibody techniques and state-of-the-art confocal laser scanning microscopy along with 3D-reconstructions will allow us to analyze the anatomical data in detail. Methodological consistency and strict criteria for identifying homologous brain structures will result in a comparable set of characters. Together with results from other members of DMP the acquired set of data will be subjected to a combined phylogenetic analysis in the concluding phase of DMP.

节肢动物大脑的许多解剖学特征在进化过程中是高度保守的，包括神经柱的存在和基本神经结构，如中央体和蘑菇体。因此，这些功能是理想的标记，从中获得节肢动物与动物王国的其他主要群体的系统发育关系。虽然真节肢动物脑结构的文献是丰富的，但只有稀疏和肤浅的报告，检查大多数其他无脊椎动物门的大脑神经节的内部结构。在“深后生动物系统发育”的开始，我们已经详细分析了真节肢动物和onychophorans的基础代表的神经结构，从而在一个更清晰的图片的地面模式的大脑的泛节肢动物。我们已经调查了几个代表环节动物的细胞解剖学，并在第二个应用期间，软体动物。该项目的目的是比较节肢动物大脑的基础模式，环节动物和软体动物。对环节动物大脑的分析已进入高级阶段，并将通过对特别感兴趣的大脑中心的详细研究加以补充。我们将继续研究基底软体动物的大脑神经节，这是一个在生物学研究所形态学项目中没有涉及的群体。使用免疫荧光抗体技术和最先进的共聚焦激光扫描显微镜沿着三维重建将使我们能够详细分析解剖数据。方法的一致性和严格的标准，以确定同源的大脑结构将导致一组可比的字符。与其他成员的结果一起，所获得的数据集将在最后阶段进行综合系统发育分析。