Comprehensive genome analysis for hematopoietic cells of atomic bomb survivors

原子弹爆炸幸存者造血细胞的综合基因组分析

• 批准号: 17H04209
• 负责人: MIYAZAKI Yasushi
• 金额: $ 9.9万
• 依托单位: Nagasaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2017
• 资助国家: 日本
• 起止时间: 2017-04-01 至 2020-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17H04209/
• 关键词: 骨髄異形成症候群; ゲノム; 原爆被爆者; 放射線; 染色体

项目成果

Persistent clonal cytogenetic abnormality with del(20q) from an initial diagnosis of acute promyelocytic leukemia.

急性早幼粒细胞白血病初步诊断显示持续性克隆细胞遗传学异常，伴有 del(20q)。

• DOI: 10.1007/s12185-019-02731-w
• 发表时间: 2020
• 期刊: International Journal of Hematology
• 影响因子: 2.1
• 作者: Fujioka M;Itonaga H;Kato T;Nannya Y;Hashimoto M;Kasai S;Toriyama E;Kamijo R;Taguchi M;Taniguchi H;Sato S;Atogami S;Imaizumi Y;Hata T;Moriuchi Y;Ogawa S;Miyazaki Y.
• 通讯作者: Miyazaki Y.

Clonal dynamics in a case of acute monoblastic leukemia that later developed myeloproliferative neoplasm.

一例后来发展为骨髓增生性肿瘤的急性单核细胞白血病病例的克隆动力学。

• DOI: 10.1007/s12185-018-2419-1
• 发表时间: 2018
• 期刊: Int J Hematol.
• 作者: Sato S;Itonaga H;Taguchi M;Sawayama Y;Imanishi D;Tsushima H;Hata T;Moriuchi Y;Mishima H;Kinoshita A;Yoshiura KI;Miyazaki Y.
• 通讯作者: Miyazaki Y.

Differing clinical features between Japanese and Caucasian patients with myelodysplastic syndromes: Analysis from the International Working Group for Prognosis of MDS

• DOI: 10.1016/j.leukres.2018.08.022
• 发表时间: 2018-10-01
• 期刊: LEUKEMIA RESEARCH
• 影响因子: 2.7
• 作者: Miyazaki, Yasushi;Tuechler, Heinz;Greenberg, Peter L.
• 通讯作者: Greenberg, Peter L.

University Medical Centre Goettingen(ドイツ)

哥廷根大学医学中心（德国）

Exome analysis of treatment-related AML after APL suggests secondary evolution.

APL 后治疗相关 AML 的外显子组分析表明二次进化。

• DOI: 10.1111/bjh.15681
• 发表时间: 2019
• 期刊: British journal of haematology
• 影响因子: 6.5
• 作者: Wang,Tianjiao;Jacoby,MeaganA;Duncavage,EricJ;Miller,ChristopherA;Heath,Sharon;Rahme,Ramy;Fenaux,Pierre;Ades,Lionel;Renneville,Aline;Cassinat,Bruno;Takeshita,Akihiro;Asou,Norio;Miyazaki,Yasushi;Kiyoi,Hitoshi;Ravandi,Farhad