Establishment of world-premier pachymeningitis animal model and development of new therapeutic option targeting TGF-beta.
Establishment of world-premier pachymeningitis animal model and development of new therapeutic option targeting TGF-beta.
批准号:
17K19663
负责人:
Kira Jun-ichi
金额:
$4.16万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Research (Exploratory)
财政年份:
2017
资助国家:
日本
项目状态:
已结题
起止时间:
2017-06-30 至 2019-03-31
中文摘要
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英文摘要
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
HLA-DRB1*04:05 allele is associated with intracortical lesions on three-dimensional double inversion recovery images in Japanese patients with multiple sclerosis
HLA-DRB1*04:05 等位基因与日本多发性硬化症患者三维双反转恢复图像上的皮质内病变相关
DOI:
10.1177/1352458517707067
发表时间:
2017
期刊:
Multiple Sclerosis Journal
影响因子:
5.8
作者:
[Shinoda Koji, Matsushita Takuya, Nakamura Yuri, Masaki Katsuhisa, Yamasaki Ryo, Yamaguchi Hiroo, Togao Osamu, Hiwatashi Akio, Kira Jun-ichi]
通讯作者:
Kira Jun-ichi
世界初の肥厚性硬膜炎動物モデル作成とTGF-βシグナルを標的とした新規治療法開発
创建世界首个肥厚性脑膜炎动物模型并开发针对TGF-β信号的新治疗方法
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[崔訳文, 眞﨑勝久, 山﨑亮, 林田翔太郎, 山口浩雄, 兵藤文紀, 江藤比奈子, 米川智, 松下拓也, 吉田眞理, Malie Malissen , Bernard Malissen , 吉良潤一]
通讯作者:
吉良潤一
Elucidation of autoimmune mechanisms and developement of novel therapy for demyelinating diseases based on genetic and envrionmental risk factors and disease-specific anti-neural antibodies
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批准号:19H01045
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$29.37万
-
财政年份:2019
-
负责人:Kira Jun-ichi
-
依托单位:
A novel model of multiple sclerosis and multiple system atrophy that are differentially manifested by the time of abnormal protein expression
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批准号:20K20470
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项目类别:Grant-in-Aid for Challenging Research (Pioneering)
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资助金额:$16.64万
-
财政年份:2019
-
负责人:Kira Jun-ichi
-
依托单位:
Elucidation of mechanisms for destruction and fixation of glia-syncytium in demyelinating diseases by whole-genome sequencing and immunohistochemical analysis.
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批准号:16H02657
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项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$30.28万
-
财政年份:2016
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负责人:Kira Jun-ichi
-
依托单位:
Induction of concentric demyelinating lesion in glia-specific connesin conditional deficient mice.
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批准号:15K15341
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2015
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负责人:Kira Jun-ichi
-
依托单位:
connexin cytopathy in the pathogenesis of demyelinating disorders
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批准号:25293204
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.9万
-
财政年份:2013
-
负责人:Kira Jun-ichi
-
依托单位:
海外基金