A novel model of multiple sclerosis and multiple system atrophy that are differentially manifested by the time of abnormal protein expression
A novel model of multiple sclerosis and multiple system atrophy that are differentially manifested by the time of abnormal protein expression
批准号:
20K20470
负责人:
Kira Jun-ichi
金额:
$16.64万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Research (Pioneering)
财政年份:
2019
资助国家:
日本
项目状态:
已结题
起止时间:
2019-06-28 至 2023-03-31
中文摘要
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英文摘要
期刊论文(55)
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Environmental risk factors for multiple sclerosis in Japanese people
日本人多发性硬化症的环境危险因素
DOI:
10.1016/j.msard.2019.101872
发表时间:
2020
期刊:
Multiple Sclerosis and Related Disorders
影响因子:
4
作者:
[Sakoda A, Matsushita T, Nakamura Y, Watanabe M, Shinoda K, Masaki K, Isobe N, Yamasaki R, Kira J.]
通讯作者:
Kira J.
Creutzfeldt-Jakob disease-like diffusion-weighted imaging hyperintensity paralleled with neuropsychiatric symptoms in a patient with limbic encephalitis associated with anti-voltage-gated potassium channel complex antibodies
与抗电压门控钾通道复合物抗体相关的边缘脑炎患者的克雅氏病样弥散加权成像高信号与神经精神症状平行
DOI:
10.1111/cen3.12525
发表时间:
2019
期刊:
Clin Exp Neuroimmunol
影响因子:
--
作者:
[Okadome T, et al.]
通讯作者:
et al.
A novel model of multiple system atrophy-cerebellar type and primary progressive mutliple sclerosis
多系统萎缩-小脑型及原发性进行性多发性硬化症的新模型
DOI:
--
发表时间:
2019
期刊:
影响因子:
--
作者:
[Masaki K, et al.]
通讯作者:
et al.
Contribution of cortical lesions to cognitive impairment in Japanese patients with multiple sclerosis
皮质病变对日本多发性硬化症患者认知障碍的影响
DOI:
10.1038/s41598-020-61012-3
发表时间:
2020
期刊:
Sci Rep
影响因子:
--
作者:
[Shinoda K, et al.]
通讯作者:
et al.
A population of inflammatory microglia exacerbates a novel mouse model of multiple system atrophy.
炎症性小胶质细胞群加剧了多系统萎缩的新型小鼠模型。
DOI:
--
发表时间:
2022
期刊:
影响因子:
--
作者:
[Dai Matsuse, Hiroo Yamaguchi, Katsuhisa Masaki, Yuji Nishimura, Tatsunori Tanaka, Toru Saiga, Kenji Tanaka, Ryo Yamasaki, Noriko Isobe, Jun-ichi Kira.]
通讯作者:
Jun-ichi Kira.
共 30 条
Elucidation of autoimmune mechanisms and developement of novel therapy for demyelinating diseases based on genetic and envrionmental risk factors and disease-specific anti-neural antibodies
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批准号:19H01045
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$29.37万
-
财政年份:2019
-
负责人:Kira Jun-ichi
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依托单位:
Establishment of world-premier pachymeningitis animal model and development of new therapeutic option targeting TGF-beta.
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批准号:17K19663
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
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资助金额:$4.16万
-
财政年份:2017
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负责人:Kira Jun-ichi
-
依托单位:
Elucidation of mechanisms for destruction and fixation of glia-syncytium in demyelinating diseases by whole-genome sequencing and immunohistochemical analysis.
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批准号:16H02657
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$30.28万
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财政年份:2016
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负责人:Kira Jun-ichi
-
依托单位:
Induction of concentric demyelinating lesion in glia-specific connesin conditional deficient mice.
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批准号:15K15341
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
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财政年份:2015
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负责人:Kira Jun-ichi
-
依托单位:
connexin cytopathy in the pathogenesis of demyelinating disorders
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批准号:25293204
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.9万
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财政年份:2013
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负责人:Kira Jun-ichi
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依托单位:
海外基金