A molecular investigation into metabolite-mediated T cell immunity

代谢物介导的 T 细胞免疫的分子研究

• 批准号: DE220101491
• 负责人: Dr Wael Awad
• 金额: $ 31.9万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-01-03 至 2025-01-02
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE220101491
• 关键词: molecular; investigation; into; metabolite; mediated

This project aims to undertake discovery research to investigate the roles of metabolites in T cell immunity. This project expects to generate new knowledge in the areas of cellular biology and immunology by using cutting-edge molecular and immunological approaches. This will provide fundamental insights into the mechanisms that govern microbial metabolite-based T cell immunity, which may advise future research into vaccines or therapeutics. In addition to knowledge gains, expected outcomes of this project include the development of innovative methodology and building international collaborations to enhance national research capabilities. This will place Australia at the forefront of conceptually innovative discovery in the life sciences.

该项目旨在进行发现性研究，以研究代谢物在T细胞免疫中的作用。该项目希望通过使用尖端的分子和免疫学方法在细胞生物学和免疫学领域产生新的知识。这将为管理基于微生物代谢物的T细胞免疫的机制提供基本见解，这可能会为未来的疫苗或治疗研究提供建议。除了获得知识外，这一项目的预期成果还包括开发创新方法和建立国际合作，以提高国家研究能力。这将使澳大利亚处于生命科学概念创新发现的前沿。