Priority Program 1316: administration and conferences

优先计划 1316：行政和会议

• 批准号: 72169378
• 负责人: Professor Dr. Michael Hensel
• 金额: --
• 依托单位: Arbeitsgruppe Mikrobiologie
• 依托单位国家: 德国
• 项目类别: Priority Programmes
• 财政年份: 2008
• 资助国家: 德国
• 起止时间: 2007-12-31 至 2015-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/72169378?language=en
• 关键词: Priority; Program; 1316; administration; conferences

The priority program 'Host-adapted metabolism of bacterial pathogens' investigates the metabolic adaptation of bacterial pathogens to host cells and organisms. The program has led to an interdisciplinary network of research groups with expertise in infection biology, bioanalytics and bioinformatics and allowed to address the complex metabolic interrelation between host and pathogen. Such analyses could previously rarely be performed due to the high demands in methodology and instrumentation. The participating groups investigate clinically important bacterial pathogens with an intracellular or extracellular lifestyle, food-borne pathogens or pathogens of plants. The isotopolog technique has a central role in many of these approaches. Due to recent advances in the sensitivity of this technique, it is now possible to analyze metabolic fluxes with high resolution during infection. A platform 'bioanalytics' was established that offers isotopolog profiling techniques demanded by a large number of participating groups. Of equally central importance is the platform 'bioinformatics' for the modelling of metabolic fluxes, for the generation of bioinformatics tools for analyses of data from metabolom and isotopolom approaches and for database generation. In April 2009, the priority program held the first international conference ‘Metabolism Meets Virulence’. The administrative project applied for should support the coordination, including an administrative assistant, travel and lumps fund for administrative support. Within the second phase from 2011 to 2014, two scientific conferences are planned, for which funding is requested. The international conference Metabolism Meets Virulence 2' should take place in 2013 and should extend international collaboration and visibility of the priority program. In 2014, a national summary symposium is planned with participation of all priority program members and additional keynote speakers.

优先项目“细菌病原体的宿主适应代谢”研究细菌病原体对宿主细胞和生物体的代谢适应。该计划导致了一个具有感染生物学，生物分析和生物信息学专业知识的研究小组的跨学科网络，并允许解决宿主和病原体之间复杂的代谢相互关系。由于对方法和仪器的要求很高，以前很少进行这种分析。参与小组调查具有细胞内或细胞外生活方式的临床重要细菌病原体，食源性病原体或植物病原体。同位素技术在许多这些方法中起着核心作用。由于该技术的灵敏度的最新进展，现在可以在感染期间以高分辨率分析代谢通量。建立了一个“生物分析”平台，提供大量参与团体所需的同位素分析技术。同样重要的是平台的“生物信息学”的代谢通量建模，生成生物信息学工具的数据分析从代谢和同位素方法和数据库生成。2009年4月，该优先计划举办了第一次国际会议“代谢遇到病毒”。申请的行政项目应支持协调，包括行政助理，差旅和行政支持的一次性资金。在2011年至2014年的第二阶段，计划举行两次科学会议，并为此申请资金。国际会议代谢遇到毒力2'应在2013年举行，并应扩大国际合作和优先计划的知名度。2014年，计划举办一次全国总结研讨会，所有优先项目成员和其他主旨发言人都将参加。