Modulation of Cortical Potential Related with Jaw Movement and Its Pato-functional Relationships in Temporomandibular Disorders

本研究旨在探讨颞下颌关节紊乱病（TMD）运动相关皮层电位的调制及其与病理功能的关系。受试者为健康对照组和颞下颌关节咔嗒声障碍（TMJ-Click）。以下颌张开运动为任务表现，用EEG和MEG诊断系统检测颞下颌关节咔哒声的病理反馈，结果表明：1）正常人随着下颌张开量的增加，准备电位增加;（2）TMJ-Click显示了大下颌时下颌张开准备电位的衰减。3)正常受试者的准备电位、下颌运动和肌肉活动之间无相关性。4)IMJ-Click显示准备电位和肌肉活动之间呈负相关。5)健康受试者显示双侧准备野的出现，包括下颌运动、张开、闭合和侧向。6)在运动领域，下颌打开显示MF的双侧出现，而侧向下颌运动显示MF在对侧感觉运动皮质区的优势。7)正常人双侧出现运动诱发场（MEF），伴随下颌张开和侧向运动。8)TMJ-Click反映了下颌运动困难程度对MF的影响，如TMJ-Click导致下颌运动受限。9)TMJ-Click的MEF较健康人明显降低，本研究旨在阐明TMJ-Click的感觉运动皮层活动与外周病理反馈之间的病理功能关系，结果表明TMD_S的反馈感觉影响皮层活动的调节。

The modulation of movement related cortical potentials of temporomandibular disorders (TMD) and its patho-functional relationship were investigated in this study. The subjects were healthy controls and TMJ clicking disorders (TMJ-Click). Jaw opening movement was used as task performance, and examination of pathological feedback from TMJ clicking was conducted with EEG and MEG diagnostic systems, and the following results were obtamed1) Healthy subjects showed increased readiness potential according to the increase of jaw openig volume. 2)TMJ-Click showed the dedaralion of jaw opening readiness potentials during large jaw qenings. 3) Healthy subjects showed no relationships among readiness potentials, inandilmiar jaw movement and muscle activities. 4) 'IMJ-Click showed a negative correlation between readiness potentials and muscle activities. 5) Healthy subjects showed the bilateral appearance of readiness fields accmpanying jaw movements, opening, c1osing, and lateral direction. 6) In the motor fields, jaw opening showed bilateral appearance of MF, while lateral jaw movements showed the predcmninance of MF in the contralateral sensorimotor cortical area to the movement side. 7) Healthy subjects showed the bilateral appearance of movement evoked fields (MEF) accompanying jaw opening and lateral movements. 8) TMJ-Click showed the modulation of MF in accordance with difficulty of jaw movement, such as restriction of the lateral jaw movement area caused by TMJ clicking. 9) TMJ-Click showed the decrease of MEF compared from that of healthy subjects.In this study, patho-functional relationships were clarifled between sensorimotor cortical activity and peripheral pathological feedback from TMJ clicking, and the findinga indicated that the feedback sensation of TMD_S affects the modulation of cortical activities.