Modulation of Cortical Potential Related with Jaw Movement and Its Pato-functional Relationships in Temporomandibular Disorders

颞下颌疾病中与下颌运动相关的皮质电位调节及其帕托功能关系

• 批准号: 09672010
• 负责人: NARITA Noriyuki
• 金额: $ 2.18万
• 依托单位: Nihon University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09672010/
• 关键词: Motion Related Cortical Potential; Magnetoencehalography; Mandibular Movement; Temporomandibular Disorder; Dipole Sources; 顎口腔機能異常; 準備電位; 運動磁界; 運動誘発磁界; 固有感覚受容性

The modulation of movement related cortical potentials of temporomandibular disorders (TMD) and its patho-functional relationship were investigated in this study. The subjects were healthy controls and TMJ clicking disorders (TMJ-Click). Jaw opening movement was used as task performance, and examination of pathological feedback from TMJ clicking was conducted with EEG and MEG diagnostic systems, and the following results were obtamed1) Healthy subjects showed increased readiness potential according to the increase of jaw openig volume. 2)TMJ-Click showed the dedaralion of jaw opening readiness potentials during large jaw qenings. 3) Healthy subjects showed no relationships among readiness potentials, inandilmiar jaw movement and muscle activities. 4) 'IMJ-Click showed a negative correlation between readiness potentials and muscle activities. 5) Healthy subjects showed the bilateral appearance of readiness fields accmpanying jaw movements, opening, c1osing, and lateral direction. 6) In the motor fields, jaw opening showed bilateral appearance of MF, while lateral jaw movements showed the predcmninance of MF in the contralateral sensorimotor cortical area to the movement side. 7) Healthy subjects showed the bilateral appearance of movement evoked fields (MEF) accompanying jaw opening and lateral movements. 8) TMJ-Click showed the modulation of MF in accordance with difficulty of jaw movement, such as restriction of the lateral jaw movement area caused by TMJ clicking. 9) TMJ-Click showed the decrease of MEF compared from that of healthy subjects.In this study, patho-functional relationships were clarifled between sensorimotor cortical activity and peripheral pathological feedback from TMJ clicking, and the findinga indicated that the feedback sensation of TMD_S affects the modulation of cortical activities.

本研究探讨了颞下颌疾病（TMD）运动相关皮质电位的调节及其病理功能关系。研究对象为健康对照和颞下颌关节点击障碍（TMJ- click）。以下颌张开运动作为任务表现，利用脑电和脑磁图诊断系统对颞下颌关节点击的病理反馈进行检查，得到以下结果：1)健康受试者随着下颌张开量的增加，准备电位增加。2)TMJ-Click显示了大下颌运动时下颌张开准备电位的衰减。3)健康被试的准备电位、不熟悉的下颌运动和肌肉活动之间没有关系。4)“IMJ-Click”与肌肉活动呈负相关。5)健康人的下颌运动、开口、闭口、侧向均出现双侧准备场。6)在运动区，下颌开口表现为双侧MF，而下颌外侧运动表现为运动侧对侧感觉运动皮质区MF的优势。7)健康受试者双侧出现运动诱发场（MEF），伴有下颌张开和侧移。8) TMJ- click显示MF随下颌运动难度的变化而变化，如TMJ click对下颌侧向运动区域的限制。9) TMJ-Click显示MEF较健康人下降。本研究阐明了颞下颌关节咔哒声引起的感觉运动皮层活动与周围病理反馈之间的病理功能关系，结果表明，颞下颌关节的反馈感觉影响皮层活动的调节。

项目成果

成田紀之,遠藤博史: "下顎運動の両側性皮質制御に関する脳磁場解析" 日本補綴歯科学会雑誌. 43・1. 111-121 (1999)

成田典之、远藤宏：“关于下颌运动的双侧皮质控制的脑磁场分析”日本修复医学会杂志 43・1（1999）。

成田紀之, 遠藤博史: "下顎運動の両側性皮質制御に関する脳磁場解析" 日本補綴歯科学会雑誌. 43. 111-121 (1999)

Noriyuki Narita、Hiroshi Endo：“关于下颌运动双侧皮质控制的脑磁场分析”日本修复医学会杂志 43. 111-121 (1999)。

成田紀之: "顎口腔機能異常者における顎運動関連脳電位-とくに顎関節有雑音者の開口準備電位について" 日本補綴歯科学会雑誌. 41・98回特別号. 62-62 (1997)

Noriyuki Narita：“与口下颌功能障碍患者的下颌运动相关的大脑电位 - 特别是颞下颌关节噪音患者的口腔准备电位”，日本口腔修复学会杂志第 41/98 期特刊（1997 年）。

Y.NAKAMURA: "Symposium on Neurobiology of Mastication-From Molecular to Systems Approach" EISEVIER SCIENCE, (1999)

Y.NAKAMURA：“咀嚼神经生物学研讨会 - 从分子到系统方法”EISEVIER SCIENCE，（1999）

N.NARITA, Y.NAKABAYASHI, M.OKUBO, T.MATSUMOTO: "Jaw-Opening-related Cortical Readiness Potentials on TMT clicking Dis-orders" Journal of Dental Research. 78.specicl lssue. (1999)

N.NARITA、Y.NAKABAYASHI、M.OKUBO、T.MATSUMOTO：“TMT 点击障碍中与张口相关的皮质准备电位”《牙科研究杂志》。