Urodynamic analysis of voiding symptoms and physiological abnormalies during voiding, which characterize benign prostatic hyperplasia.
对排尿症状和排尿期间生理异常进行尿动力学分析,这是良性前列腺增生的特征。
基本信息
- 批准号:09671604
- 负责人:
- 金额:$ 1.86万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (C)
- 财政年份:1997
- 资助国家:日本
- 起止时间:1997 至 1999
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
With benign prostatic hyperplasia (BPH), lower urinry tract symptoms, such as retardation and nocturia, are associated. WHO recommends to score the seven specified symptoms (IPSS) for grading the severity of BPH. IPSS is useful to evaluate the clinical outcomes of many kinds of therapy on BPH in the same patients. However, it has been proved that IPSS does not reflect the extent to which the prostate is enlarged or to which the lower urinary tract is obstructed. In short, IPSS is not a well-established diagnostic scale. We have perfomed urodynamnic testings in detail and found characteristic urodynamic findings in BPH and studied the relationship between such findings and lower urinary tract symptoms which are commonly found in BPH.We have made, from the results of our series of urodynamic studies, a scoring scale for BPH (SPSS). Using this scale in 30 cases of BPH, we studied differences between IPSS and SPSS from the standpoint of age, prostate volume (as measured on echogram), uroflowmetry, pressure/flow study, A-G nomogram, Schaefer's obstruction prameters and residual urine volume.The maximum flow rate (Q max) and the average flow rate (Q ave) were found correlating significantly with SPSS, but not with IPSS. This proves that SPSS reflects urodynamic conditions, or objective findings, more than IPSS. Neither SPSS nor IPSS was related with Schaefer's obstruction parameters or A-G nomogram. These two scales were not correlated with total prostate volume and adenoma volume. There was a correlation between A-G nonmogram or Schaefer's nomograim and total prostate volume. This means that the lower urinary tract is obstructed by prostatic enlorgement. However, it remains to be explained why SPSS was correlated with uroflowmetric parameters, but not with obstraction parameters.
良性前列腺增生(BPH)与下尿路症状,如发育迟缓和排尿困难有关。WHO建议对BPH的七种特定症状(IPSS)进行评分,以分级BPH的严重程度。国际前列腺症状评分可用于评价同一患者多种治疗方法的疗效。然而,已经证明IPSS不能反映前列腺增大或下尿路阻塞的程度。简而言之,IPSS不是一个完善的诊断量表。我们对BPH患者进行了详细的尿动力学检查,发现了BPH患者的特征性尿动力学表现,并研究了这些表现与BPH常见下尿路症状的关系,根据我们的一系列尿动力学检查结果,编制了BPH评分量表(SPSS)。应用该量表对30例BPH患者的年龄、前列腺体积(超声测量)、尿流率、压力/流量、A-G列线图、Schaefer's梗阻参数、残余尿量等指标进行比较,发现最大尿流率(Qmax)和平均尿流率(Qave)与SPSS有显著相关性,而与IPSS无显著相关性。这证明SPSS比IPSS更能反映尿动力学状况或客观结果。SPSS和IPSS与Schaefer梗阻参数和A-G列线图均无相关性。这两个量表与前列腺总体积和腺瘤体积无关。前列腺体积与A-G非线性图及Schaefer非线性图有相关性。这意味着下尿路被前列腺增生阻塞。然而,它仍然是有待解释的,为什么SPSS与尿流率参数,但不与梗阻参数。
项目成果
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Sakakibara,R: "stress-induccol urinary incontinence in patients with spinocerebellar degeneration" J Neurlo Neurosurg Ps. (in press).
Sakakibara,R:“脊髓小脑变性患者的压力诱导性尿失禁”J Neurlo Neurosurg Ps。
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Sakakibara,R: "Micturitional distarbance in a patients with Guillain-Berre syndrome" J Neurol Neurosurg Ps. (in press).
Sakakibara,R:“格林-贝尔综合征患者的排尿障碍”J Neurol Neurosurg Ps。
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服部孝道,安田耕作,山西友典,榊原隆次: "神経疾患による排尿障害ハンドブック" 三輪書店, 345 (1998)
Takamichi Hattori、Kousaku Yasuda、Tomonori Yamanishi、Ryuji Sakakibara:“神经系统疾病引起的泌尿系统疾病手册”Miwa Shoten,345(1998)
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安田耕作(分担): "泌尿器科診療Q&A(神経因性膀胱)" 六法出版社, 1667(1064-1067) (1998)
安田耕作(撰稿人):《泌尿外科治疗 Q&A(神经性膀胱)》 六穗出版社,1667(1064-1067)(1998 年)
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安田耕作 分担: "泌尿器科診断Q&A 神経因性膀胱"六法出版社. 1064-1067 (1998)
Kosaku Yasuda 撰稿人:《泌尿外科诊断问答神经源性膀胱》Rokuho Publishing 1064-1067 (1998)。
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YASUDA Kosaku其他文献
YASUDA Kosaku的其他文献
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{{ truncateString('YASUDA Kosaku', 18)}}的其他基金
Change of autonomic nerve receptor in geriatric micturitional disturbance
老年排尿障碍自主神经受体的变化
- 批准号:
03670745 - 财政年份:1991
- 资助金额:
$ 1.86万 - 项目类别:
Grant-in-Aid for General Scientific Research (C)
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