STUDY ON RESIN DIRECT PULP CAPPING OF INFECTED DENTAL-EFFECT OF DENTIN BONDING SYSTEM AND HIGH OXIDATION POTENTIAL WATER-

树脂直接盖髓术对感染牙体牙本质粘结体系及高氧化电位水的影响研究

• 批准号: 09671961
• 负责人: KUDOU Yoshiyuki
• 金额: $ 2.11万
• 依托单位: IWATE MEDICAL UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09671961/
• 关键词: DIRECT PULP CAPPING; INFECTED PULP; 4-META; MMA-TBB; HIGH OXIDATION POTENTIAL WATER; VNCOMYCIN; 4META; MMA-TBB

The possibility of direct pulp capping of infected dental pulp with resin bonding material which added antibacterial agents (vancomycin, metronidazol, HY-agent) was examined. The effect of application of high oxidation potential water, used as a disinfectant instead of the chemical surgery, on bond strength to dentin was examined. The following were obtained : By only treatment of high oxidation potential water, the good adhesion was not obtained to dentin. The good adhesion was obtained by appropriate combination of processing time and method of processing of 10-3 treatment (10% citric acid and 3% FeCl_2) and high oxidation potential water.In the vital pulp of maxilla posterior tooth of the Wistar rat, which contaminated with A.naeslundii, the pulp reaction capped with resin bonding agent which added antibacterial agents (2% vancomycin) was histopathologically examined. Though some of these examples recognized abscess formation, when bonding material added no antibacterial agent was used, abscess formation could not be recognized, when bonding material added antibacterial agent was used. In present experiment, the effect of using high oxidation potential water jointly could not be accepted.

用添加抗菌剂(万古霉素、甲硝唑、HY-剂)的树脂粘结材料对感染牙髓进行直接盖髓。用高氧化电位水代替化学手术作为消毒剂，研究其对牙本质粘结强度的影响。结果表明：仅用高氧化电位水处理牙本质不能获得良好的粘附性。10-3处理(10%柠檬酸和3%FeCl2)和高氧化电位水的处理时间和处理方法的适当组合可获得良好的粘附性。在被内氏假丝酵母菌污染的Wistar大鼠上颌后牙活髓中，用添加抗菌剂(2%万古霉素)的树脂粘结剂封盖牙髓进行组织病理学检查。虽然这些例子中有一些可以识别出脓肿的形成，但当粘结材料中没有添加抗菌剂时，当粘结材料中添加了抗菌剂时，无法识别脓肿的形成。在本实验中，高氧化电位水联合使用的效果是不能接受的。

项目成果

子田晃一、松村英雄、福島久典: "抗菌剤の科学と臨床応用 (分担執筆)" 日本歯科評論社, 197 (1998)

Koichi Koda、Hideo Matsumura、Hisanori Fukushima：“抗菌剂的科学与临床应用（合著者）” Nippon Dental Hyoronsha，197（1998）

Yoshiyuki KUDOU,Kenichi OBARA,Toshihiro KAWASHIMA,Minoru KUBOTA: "Effects of Adding Agents to Commercial MMA-TBB Dentin Bonding System Part 2.Autibacterial Effect(In Japanese)" Japan.J.Conserv.Dent.Vol.42(Spring Issue). 20 (1999)

Yoshiyuki KUDOU、Kenichi OBARA、Toshihiro KAWASHIMA、Minoru KUBOTA：“添加剂对商业 MMA-TBB 牙本质粘接系统的影响第 2 部分.Autibacterial 效应（日文）” Japan.J.Conserv.Dent.Vol.42（春季号）

工藤義之 他: "市販MMA-TBB系象牙質接合材に対する添加剤の効果 第二報 : 抗菌性について" 日本歯科保存学会雑誌. 42, 春季特別. p-20 (1999)

Yoshiyuki Kudo 等人：“添加剂对市售 MMA-TBB 牙本质粘合材料的影响，第二份报告：关于抗菌性能”，日本保守牙科学会杂志 42，Spring Special。

Yoshiyuki Kudou: Science of Antibiotics and its clinical application. Nihon Shika Hyouronsha, 8-18 (1998)

Yoshiyuki Kudou：抗生素科学及其临床应用。

工藤 義之 他: "市販MMA-TBB系象牙質接合材に対する添加剤の効果 第二報:抗菌性について" 日本歯科保存学会雑誌. 42,春季特別. 20 (1999)

Yoshiyuki Kudo 等人：“添加剂对市售 MMA-TBB 牙本质粘合材料的影响。第二次报告：抗菌性能”，日本保守牙科学会杂志 42，春季特刊。