GRK 1167: Cell-cell Communication in Neural and Immune Systems: Topological Organisation of Signal Transduction
GRK 1167: Cell-cell Communication in Neural and Immune Systems: Topological Organisation of Signal Transduction
批准号:
812229
负责人:
金额:
$0.0万
依托单位国家:
德国
项目类别:
Research Training Groups
财政年份:
2005
资助国家:
德国
项目状态:
已结题
起止时间:
2004-12-31 至 2013-12-31
中文摘要
细胞间的通讯是多细胞生物必不可少的生物学功能。细胞间通讯的各种基本机制在系统发育过程中进化而来,这些机制受到器官、组织和细胞类型特异性适应的影响。研究训练组的目标是研究和比较免疫系统和神经系统中细胞通讯和信号转导的分子机制,并通过跨学科教育使该计划的学生具备在这两个生物学领域进行顶级研究的资格。该方案以马格德堡建立的两个主要生物医学研究领域的科学潜力为基础,即免疫学和神经科学,这两个领域在国际上都得到高度认可。该方案包括来自奥托·冯·格里克大学医学院和自然科学系以及莱布尼茨神经生物学研究所的科学家。
英文摘要
Communication between cells is an essential biological function in multi-cellular organisms. Various basic mechanisms of cell-cell communication have evolved during phylogenesis, which were subject to organ-, tissue and cell type-specific adaptation. It is the aim of the Research Training Group to study and compare molecular mechanisms of cellular communication and signal transduction in the immune and the nervous systems, and to qualify students of the programme for top-level research by interdisciplinary education in both biological fields. The programme is based on the scientific potential of the two major biomedical research areas established in Magdeburg, i.e. Immunology and Neurosciences, which both are highly recognised at the international level. The programme includes scientists from the faculties of Medicine and Natural Sciences of the Otto von Guericke University and from the Leibniz Institute for Neurobiology.
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DOI:
10.1016/j.neuint.2012.02.031
发表时间:
2012-05-01
期刊:
NEUROCHEMISTRY INTERNATIONAL
影响因子:
4.2
作者:
[Li, Rongyu, Zhu, Zhihui, Reiser, Georg]
通讯作者:
Reiser, Georg
DOI:
10.1371/journal.pone.0040853
发表时间:
2012-07-16
期刊:
PLOS ONE
影响因子:
3.7
作者:
[Lipka, Daniel B., Wagner, Marie-Christine, Fischer, Thomas]
通讯作者:
Fischer, Thomas
DOI:
10.1038/s41598-018-21839-3
发表时间:
2018-02-27
期刊:
Scientific reports
影响因子:
4.6
作者:
[Bharate JB, McConnell N, Naresh G, Zhang L, Lakkaniga NR, Ding L, Shah NP, Frett B, Li HY]
通讯作者:
Li HY
3,4-Diarylmaleimides—a novel class of kinase inhibitors—effectively induce apoptosis in FLT3-ITD-dependent cells
3,4-二芳基马来酰亚胺——一类新型激酶抑制剂——有效诱导 FLT3-ITD 依赖性细胞凋亡
DOI:
10.1007/s00277-011-1311-3
发表时间:
2012
期刊:
Annals of Hematology
影响因子:
3.5
作者:
[Heidel FH, Mack TS, Razumovskaya E, Blum MC, Lipka DB, Ballaschk A, Kramb JP, Plutizki S, Rönnstrand L, Dannhardt G, Fischer T]
通讯作者:
Fischer T
DOI:
10.4049/jimmunol.1302585
发表时间:
2014-04-01
期刊:
JOURNAL OF IMMUNOLOGY
影响因子:
4.4
作者:
[Korthals, Mark, Schilling, Kerstin, Fischer, Klaus-Dieter]
通讯作者:
Fischer, Klaus-Dieter
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