STUDY ON NON-INVASIVE MEASUREMENT OF ANISOTROPIC RESIDUAL STRESS IN BONE AND FUNCTIONAL DESIGN OF IMPLANT

骨各向异性残余应力的无创测量及种植体的功能设计研究

• 批准号: 09650153
• 负责人: SHIBANO Jun-ichi
• 金额: $ 2.43万
• 依托单位: HOKKAIDO UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09650153/
• 关键词: Biomechanics; Residual Stress; Anisotropy; Bone Structure; X-ray Method; Non-invasive Measurement; Finite Element Method; Bone Remodeling; 非破壊評価; 白色X線法

(1) A method to measure the anisotropic residual stress in compact bone was constructed using the polychromatic X-ray diffraction method. The residual stress in the compact bone of bovine diaphysis was measured by this method. To observe the difference of region, the specimen was taken from the middle region of bovine diaphysis divided into four parts : anterior, posterior, medial, lateral, at each bone axial and circumferential direction. As a result, the tensile residual stress of 42MPa was found in the bone axial direction at posterior part of the bovine femoral bone. The anisotropic residual stress in the bone could be evaluated nondestructively by this method.(2) A non-invasive measurement method of the residual stress in the bone using the characteristic X-ray diffraction was proposed. The residual stress in the tibia of rabbit was measured in vivo by this method. As a result, the tensile residual stress of 36MPa was found in the bone axial direction of the rabbit tibia. It was c … More onfirmed that this method was very useful for the non-invasive measurement of the residual stress in the bone.(3) A polychromatic X-ray method to measure nondestructively three dimensional residual stress occurred in the coating implant with the intermediate layer was presented. The residual stress of hydroxyapatite coating titanium implant with the titania intermediate layer, made by atmospheric plasma-spray processing, was measured by this method. As a result, it was found that the compressive residual stress in the coating layer of the coating implant with the intermediate layer was smaller than that of the implant coated only with hydroxyapatite.(4) The adaptive bone remodeling phenomenon was analyzed using the three dimensional finite element method on two important clinical problem ; a proximal femur after prosthetic total hip joint replacement (THR) and vertebral bodies fixed by the anterior spinal instrumentation (SI). On the THR simulation, a normal hip joint model which composed of the proximal femur and the pelvic bone including femoral head and acetabular was constructed three-dimensionally. On the simulation of spinal instrumentation, a normal lumbar spine model which composed three vertebral bodies and four intervertebral discs was constructed three-dimensionally. As a result, the remodeling simulation showed that the bone density and the stress decreased significantly at cancellous bone around bone-implant interface. Less

(1)建立了用多色x射线衍射法测量致密骨各向异性残余应力的方法。用该方法测定了牛骨干致密骨的残余应力。为了观察区域的差异，从牛骨干中部取标本，在每个骨轴向和周向分为前、后、内、外侧四部分。结果表明，牛股骨后侧骨轴向残余拉伸应力为42MPa。该方法可对骨内各向异性残余应力进行无损测量。(2)提出了一种基于特征x射线衍射的骨内残余应力无创测量方法。用该方法测定了家兔胫骨的体内残余应力。结果表明，兔胫骨骨轴向的拉伸残余应力为36MPa。进一步证实了该方法对于骨内残余应力的无创测量是非常有用的。(3)提出了一种多色x射线无损测量含中间层涂层植入体三维残余应力的方法。用该方法测量了常压等离子喷涂法制备的羟基磷灰石涂层钛种植体的残余应力。结果发现，有中间层的涂层种植体的涂层层内的残余压应力小于仅有羟基磷灰石涂层的种植体。(4)应用三维有限元法分析了临床两个重要问题的适应性骨重塑现象；假体全髋关节置换术（THR）后的股骨近端和前路脊柱内固定（SI）固定的椎体。在THR模拟中，构建了一个由股骨近端和骨盆骨（包括股骨头和髋臼）组成的三维正常髋关节模型。在模拟腰椎内固定的基础上，建立了由3个椎体和4个椎间盘组成的正常腰椎三维模型。结果表明，骨-种植体界面周围松质骨的骨密度和应力显著降低。少

项目成果

Masahiro TODOH, 他3名: "Anisotropic Residual Stress of Bovine Femoral Bone" Proceedings of the International Conference on New Frontiers in Biomechanical Engineering. 459-462 (1997)

Masahiro TODOH 等 3 人：“牛股骨各向异性残余应力”生物力学工程新前沿国际会议论文集 459-462 (1997)。

Masahiro TODOH, 他1名: "X-Ray Measurements of Anisotropic Residual Stress in Bovine Femoral Bone" Proceedings of the 9th International Comference on Biomedical Engineering. 698-700 (1997)

Masahiro TODOH 等 1 篇：“牛股骨各向异性残余应力的 X 射线测量”第九届国际生物医学工程会议记录 698-700 (1997)。

Masahiro TODOH et al.: "Polychromatic X-RAy Measurements of Anisotropic Residual Stress in Bovine Femoral Bone" Trans.Jpn.Soc.Mech.Eng.65-630, A.406-413 (1999)

Masahiro TODOH 等人：“牛股骨各向异性残余应力的多色 X 射线测量” Trans.Jpn.Soc.Mech.Eng.65-630，A.406-413 (1999)

東藤正浩, 他1名: "X線による骨組織の残留応力測定" 第12回北海道整形外科基礎研究会講演論文集. 14-14 (1998)

Masahiro Higashito 等 1：“使用 X 射线测量骨组织中的残余应力”第 12 届北海道骨科基础研究会议论文集 14-14（1998 年）。

東藤正浩, 他3名: "牛大腿骨内異方性残留応力の白色X線測定" 日本機械学会論文集(A編). 65-630. 406-413 (1999)

Masahiro Todo 等 3 人：“牛股骨各向异性残余应力的白色 X 射线测量”日本机械工程师学会会议录（A 版）406-413（1999 年）。