Cryosuit - Portable body cooling for heat illness

全球有7亿人暴露在危及生命的极端高温下（欧盟委员会，2017年）。到2030年，由于气候变化的影响，热应激将使全球经济损失2.4万亿美元/年（联合国），与热相关的死亡人数将增加257%（英国公共卫生，2014年）。中暑是世界各地发病率和死亡率的重要来源，并且与昂贵的长期康复需求相关。这是一个不可避免的日益严重的问题，需要一个快速的、以技术为主导的解决方案。便携式制冷技术的开发和实施将是减轻全球人口中暑指数上升的影响不可或缺的一部分。中暑是一种严重的疾病，由于暴露于炎热的环境和/或在炎热的环境中进行体力劳动而发生。这是一种医疗紧急情况，如果你的核心温度没有迅速降低，可能是致命的。目前，最有效的治疗方法是全身冰浴，但由于储存和运输方面的资源量和后勤复杂性，在绝大多数情况下无法实施。需要运输到医疗机构，导致治疗延误，大大增加发病率和死亡率的可能性。Cryosuit克服了当前治疗方法所遇到的关键后勤和性能问题，并提供了一种紧凑，轻便，按需冷却装置，能够在任何情况下部署。冷冻衣就是你背包里的冰浴。我们正在申请专利的技术旨在模拟冰水浸泡，只需一小部分资源。一种强大的冷却剂储存在紧凑的便携式罐中，注入粘附在身体上的导电垫，提供救生冷却。Cryogenx团队拥有20多年的医疗经验和热病管理方面的专业知识。我们对热病的病理生理学、体温调节机制和创新的冷却技术有全面的了解。我们得到了世界领先的环境医学科学家的支持，并在体育、国防和医疗保健领域建立了广泛的商业联系。该项目的范围旨在快速开发高保真原型，并验证其功效和安全性，证明我们的技术可以融入安全有效的产品中。实现这些里程碑将使我们能够通过获取医疗器械认证所需的数据集来快速商业化，并通过临床疗效验证来利用潜在客户。

Globally 700 million people are exposed to life-threatening extreme heat (European Commission,2017). By 2030, due to the effects of climate change, heat stress will cost the global economy $2.4trn/year (UN), and heat-related deaths will increase by 257% (Public Health England,2014). Heat illness constitutes a significant source of morbidity and mortality across the world, and is associated with costly, long-term rehabilitation requirements. This is an inescapably growing issue that requires a rapid, technology-led solution. The development and implementation of portable cooling technology will be integral to mitigate the exponentially rising impact of heat illness on global populations.Heat illness is a serious condition which occurs as a result of exposure to, and/or physical exertion in hot environments. It's a medical emergency and can be fatal if your core temperature is not rapidly reduced. Currently, the most effective treatment method is a full-body ice bath, however the volume of resources and logistical complications regarding storage and transportation renders it impossible to implement in the vast majority of scenarios. Transportation to medical facilities is required, leading to delays in treatment, significantly increasing the likelihood of morbidity and mortality.Cryosuit overcomes the critical logistical and performance issues experienced with current treatment methods and provides a compact, lightweight, on-demand cooling device able to be deployed in any scenario. Cryosuit is the ice bath in your backpack. Our patent pending technology is designed to emulate ice water immersion, with a fraction of the resources. A powerful coolant stored within compact, portable canisters is injected into conductive pads adhered to the body, delivering life-saving cooling.The Cryogenx team has 20+ years medical experience and specialist expertise in heat illness management. We have comprehensive knowledge of the pathophysiology of heat illness, thermoregulatory mechanisms and innovative cooling technologies. We have support from the world's leading environmental medicine scientists, and have developed extensive commercial links into the sports, defence, and healthcare sectors.The scope of this project aims to rapidly develop high-fidelity prototypes and validate their efficacy and safety, proving that our technology can be incorporated into a safe and effective product. Achieving these milestones will enables us to rapidly commercialise through acquiring the necessary data-set for medical device certification, and leverage prospective clients through clinical efficacy validation.