Developmental Core

项目摘要 第三海岸CFAR核心B：辅助核心（DC） 第三海岸艾滋病研究中心（TC CFAR）发展核心（DC）作为基金会， 其成员建立新的NIH资助的研究，推进行政核心（AC）优先的科学 施政纲要的演讲DC服务能够实现并推动TC CFAR的每个总体目标。DC提供了一系列的种子 资助机制为所有教师（核心资助奖），教师新的艾滋病毒研究（试点奖），我们的 科学核心（核心资源奖）和社区合作伙伴（社区合作和社区 迷你奖）。DC在行政补充（AS）的竞争中取得了成功，并协助AC 其他机制。在最初的5年里，通过多个DC机制获得了560多万美元， AS，其中> 860 000美元由NU和UC从机构支助中捐款。在不到5年的时间里， 这些投资一直很强劲。三个总体目标的项目均由DC奖资助 总体目标2和3是最近由行政协调会领导的战略规划提出的 总体目标1。这里提议的发展中国家工作增加了发展中国家供资项目的预期增长， 目标2和3。艾滋病毒研究的新参与者和向DC提交的跨学科报告有所增加。 社区合作奖与HRSA资助的社区合作伙伴组织建立了关系， 沿着从行政补充提案制定过程中学习， 响应终止艾滋病毒流行（EHE）倡议，并成功推出新的EHE科学 工作组，开始种子更多的研究实践伙伴关系。强大的指导是另一个DC 一项有助于初级教师职业发展的服务，正在芝加哥大学开展艾滋病毒研究， 并开始提高URM教师在CFAR中的代表性。新的跨机构和跨- 学科NHLBI资助的职业发展计划（第三海岸艾滋病毒相关的心血管和睡眠 K12职业发展计划）正在协同促进非艾滋病共病研究的未来增长 以及我们教师的职业生涯初级教师获得DC审查小组的经验，核心现在也将 指导一位新的联合主任，并给予初级教师实现独立的NIH资金领导经验， 轮流担任联合导演DC还将CFAR成员引导到增强提案和项目的资源 开发，包括DC提交前后的指导以及NIH之前的模拟研究部分审查 意见书。更新的目的是：（1）向技术合作和财务报告委员会成员提供种子资金， 阶段调查员（ESI）和建立了新的艾滋病毒研究的教师，以进一步加强高度优先的艾滋病毒 （2）通知和资助现有和新的社区合作伙伴提供公共卫生，预防， 护理服务，包括那些应对推动艾滋病毒流行的结构性不平等的服务;（3）加强职业生涯 发展，并改善导航，以增强艾滋病毒研究的新进入者和我们的专业知识 科学优先。

PROJECT SUMMARY THIRD COAST CFAR CORE B: DEVELOPMENTAL CORE (DC) The Third Coast Center for AIDS Research (TC CFAR) Developmental Core (DC) serves as the foundation from which members build new NIH-funded research that advances the Administrative Core (AC)-prioritized scientific agenda. DC services enable and fuel each of the TC CFAR Overall aims. The DC provides a range of seed funding mechanisms for all faculty (Core Subsidy Awards), faculty new to HIV research (Pilot Awards), our scientific Cores (Core Resource Awards), and community partners (Community Collaborative and Community Mini-Awards). DC has enabled success in competitions for administrative supplements (AS) and assists AC with other mechanisms. In the first 5 years, more than $5.6 million was awarded via multiple DC mechanisms and AS, with >$860,000 of that total contributed by NU and UC from institutional support. In less than 5 years, returns on these investments have been strong. Projects on each of the 3 Overall aims have been funded by DC Awards and Administrative Supplements; Overall aims 2 and 3 emerged from AC-led strategic planning more recently than Overall aim 1. DC work proposed here adds to anticipated growth in DC-funded projects addressing Overall aims 2 and 3. New entrants to HIV research, and trans-disciplinary submissions to the DC, have increased. Community Collaborative Awards built relationships with HRSA-funded community partner organizations that, along with learning from processes for Administrative Supplement proposal development, enabled a strong response to the Ending the HIV Epidemic (EHE) Initiative and the successful launch of new EHE Scientific Working Group that is starting to seed more research-practice partnerships. Strong mentorship is another DC service that contributes to junior faculty career development, is growing HIV research at University of Chicago, and starting to improve representation of URM faculty across the CFAR. A new cross-institutional and cross- disciplinary NHLBI-funded career development program (Third Coast HIV-related Cardiovascular and Sleep Disorders K12 Career Development Program) is synergizing future growth of non-AIDS co-morbidities research as well as our faculty’s careers. Junior faculty gain DC review panel experience, and the Core will now also mentor a new co-director and give junior faculty achieving independent NIH funding leadership experience as a rotating co-director. The DC also navigates CFAR members to resources that enhance proposal and project development, including mentoring before and after DC submissions and mock study section reviews prior to NIH submissions. The aims of this renewal are: (1) to provide seed funding to TC CFAR members, emphasizing early stage investigators (ESI) and established faculty new to HIV research, to further enhance high priority HIV research; (2) to inform and fund current and new community partners providing public health, prevention, and care services, including those countering structural inequities driving the HIV epidemic; (3) to enhance career development, and improve navigation to proposal-enhancing expertise for new entrants to HIV research and our scientific priorities.