Training Grant in Pediatric Endocrinology, Diabetes and Metabolism

项目总结 此续签申请要求继续支持我们的NIH机构培训补助金(T32)在儿科 哥伦比亚大学韦格洛斯内科医学院(CUIMC)内分泌学博士。这笔赠款将允许 儿科内分泌科将继续1)加强和发展研究培训机会 儿科内分泌学满足国家的优先事项，培训儿科内分泌学的研究人员 在实验室、临床和转化型研究中担任领导角色3)培养一支干部队伍 儿科内分泌学家的未来学术生涯将有助于填补中国严重短缺的研究人员 儿童糖尿病/肥胖症和4)使研究人员做好准备，以满足持续的国家卫生优先事项/目标 包括糖尿病、母婴和儿童健康，以及超重/代谢障碍。这些目标是 在我们的ACGME批准的儿科内分泌学奖学金中完成三年的培训后获得。 此外，选定的研究员将有资格担任肥胖医学委员会的成员。 这五个研究领域是：i.肥胖/临床和分子糖尿病，ii.相互关系和障碍 雄激素/生长因子/脂代谢，III。身体成分与代谢性骨病，IV。 与儿科相关的环境内分泌干扰物和诉个性化医学/遗传学/细胞生物学 内分泌学。该方案包括生物统计学、信息学、流行病学、代谢组学/ 微生物学，伦理学和人类研究，拨款撰写，药物动力学，分子和细胞生物学 所需的教学课程和职业指导。34名培训教员中包括30名理工科教师 导师、4名咨询教员、1名生物统计学家/流行病学家、1名儿科研究副院长和1名 学院发展副主席，全部来自多个相互关联的部门。 哥伦比亚大学被指定为刚果民主共和国研究中心，并拥有 获得了CTSA对翻译研究的原始资助。因此，NIH扩展了该应用 支持的以患者为中心的研究和临床研究方法硕士项目 支持KL2导师职业发展计划和试点CTSA奖项。中集集团致力于 招聘妇女和少数族裔申请者和职业发展。此请求是为了继续 每年资助3个奖学金实习生职位，为期5年。多亏了这笔培训补助金和强者 除了我们已经开发的课程，我们继续招募优秀的申请者完成他们的儿科 并寻求发展他们在儿科内分泌学和糖尿病方面的研究技能。

PROJECT SUMMARY This renewal application requests continued support of our NIH Institutional training grant (T32) in Pediatric Endocrinology at Columbia University, Vagelos College of Physicians & Surgeons (CUIMC). This grant will allow the Division of Pediatric Endocrinology to continue to 1) enhance and develop research training opportunities in pediatric endocrinology 2) meet the national priorities of training investigators in pediatric endocrinology who will be available to assume leadership roles in laboratory, clinical and translational based research 3) create a cadre of pediatric endocrinologists whose future academic careers will help fill the critical shortage of investigators in pediatric diabetes/obesity and 4) prepare investigators to meet the continuing national health priorities/objectives including Diabetes, Maternal Infant and Child Health, and Overweight/Metabolic Disorders. These goals are achieved by completion of three years of training in our ACGME approved Pediatric Endocrinology fellowship. In addition, select fellows will be qualified to sit for the Obesity Medicine Boards. The five areas of investigation are i. Obesity/Clinical and Molecular Diabetes, ii. Interrelationships and Disorders of Androgen/Growth Factors/Lipid Metabolism, iii. Body Composition and Metabolic Bone Disease, iv. Environmental Endocrine Disruptors and v. Personalized Medicine/Genetics/Cell Biology, as related to Pediatric Endocrinology. The program includes training in biostatistics, informatics, epidemiology, metabolomics/ microbiomics, ethics and human research, grant writing, pharmacokinetics, molecular and cellular biology with required didactic coursework and career guidance. The 34 training faculty preceptors include 30 scientific mentors, 4 consultative faculty, 1 biostatistician/epidemiologist, 1 Associate Dean of Pediatric Research and 1 Vice Chair of Faculty Development, all from multiple interrelated divisions. The institution’s commitment to research is exemplified by Columbia having been designated a DRC and having received an original CTSA grant for translational research. This application is augmented thus by an NIH supported CTSA, a Master’s Program in Patient Oriented Research and Clinical Research methods and a CTSA supported KL2 Mentored Career Development Program and pilot CTSA awards. CUIMC is committed to the recruitment of women and minority applicants and career development. This request is made for continued funding of 3 fellowship trainee positions per year for a 5 year award. Thanks to this training grant and the strong program we have developed, we continue to recruit outstanding applicants who have completed their pediatric residency and seek to develop their research skills in Pediatric Endocrinology and Diabetes.