Training Grant in Pediatric Endocrinology, Diabetes and Metabolism

 描述（由申请人提供）：此更新申请要求继续支持我们的NIH机构培训补助金（T32）在哥伦比亚大学，内科医生和外科医生学院（CNOC）的儿科内分泌学。这笔赠款将使儿科内分泌科继续1）加强和发展儿科内分泌学的研究培训机会2）满足培训儿科内分泌学研究者的国家优先事项，这些研究者将在临床/实验室转化研究中担任领导角色3）培养一批儿科内分泌学家，他们未来的学术生涯将有助于填补儿科糖尿病/肥胖症研究人员的严重短缺;使医务人员做好准备，以实现持续的国家卫生优先事项/目标，包括糖尿病、母婴健康和超重/代谢紊乱。这些目标是通过在我们ACGME批准的儿科内分泌学奖学金完成三年的培训来实现的。仅要求为两年的儿科内分泌学相关领域的研究提供资金。调查的五个领域是临床和分子糖尿病/肥胖，雄激素/生长因子/脂质代谢的相互关系和疾病，身体成分和代谢性骨病，环境内分泌干扰物和遗传学/细胞生物学，与儿科内分泌学有关。该计划包括生物统计学，流行病学，伦理学和人类研究，赠款写作，药代动力学，分子和细胞生物学方面的培训，并提供必要的教学课程和职业指导。培训教师包括25名科学导师，8名咨询教师，1名生物统计学家/流行病学家，1名儿科研究副院长和1名教师发展副主席，所有这些都来自多个相互关联的部门。该机构对研究的承诺体现在哥伦比亚已被指定为DRC，并已收到原始CTSA赠款的转化研究。因此，该应用程序得到了NIH支持的CTSA，以患者为导向的研究和临床研究方法硕士课程以及CTSA支持的K12指导职业发展计划和试点CTSA奖项的支持。该委员会致力于招聘妇女和少数族裔申请人和职业发展。这项请求是为了继续每年为3个研究金受训人员职位提供资金，为期5年。由于这项培训补助金和我们开发的强大计划，我们将继续招募已完成儿科住院医师培训的优秀申请人，并寻求发展他们在儿科内分泌学和糖尿病方面的研究技能。

 DESCRIPTION (provided by applicant): This renewal application requests continued support of our NIH Institutional training grant (T32) in Pediatric Endocrinology at Columbia University, College of Physicians & Surgeons (CUMC). This grant will allow the Division of Pediatric Endocrinology to continue to 1) enhance and develop research training opportunities in pediatric endocrinology 2) meet the national priorities of training investigators in pediatric endocrinology who will be available to assume leadership roles in clinical/laboratory translational based research 3) create a cadre of pediatric endocrinologists whose future academic careers will help fill the critical shortage of investigators in pediatric diabetes/obesity and 4) prepare investigatrs to meet the continuing national health priorities/objectives including Diabetes, Maternal Infant and Child Health, and Overweight/Metabolic Disorders. These goals are achieved by completion of three years of training in our ACGME approved Pediatric Endocrinology fellowship. Funding is requested only for the two years devoted to research in fields relevant to pediatric endocrinology. The five areas of investigation are Clinical and Molecular Diabetes/Obesity, Interrelationships and Disorders of Androgren/Growth Factors/Lipid Metabolism, Body Composition and Metabolic Bone Disease, Environmental Endocrine Disruptors and Genetics/Cell Biology, as related to Pediatric Endocrinology. The program includes training in biostatistics, epidemiology, ethics and human research, grant writing, pharmacokinetics, molecular and cellular biology with required didactic coursework and career guidance. The training faculty includes 25 scientific mentors, 8 consultative faculty, 1 biostatistician/epidemiologist, 1 Associate Dean of Pediatric Research and 1 Vice Chair of Faculty Development, all from multiple interrelated divisions. The institution s commitment to research is exemplified by Columbia having been designated a DRC and having received an original CTSA grant for translational research. This application is augmented thus by an NIH supported CTSA, a Master s Program in Patient Oriented Research and Clinical Research methods and a CTSA supported K12 Mentored Career Development Program and pilot CTSA awards. CUMC is committed to the recruitment of women and minority applicants and career development. This request is made for continued funding of 3 fellowship trainee positions per year for a 5 year award. Thanks to this training grant and the strong program we have developed, we continue to recruit outstanding applicants who have completed their pediatric residency and seek to develop their research skills in Pediatric Endocrinology and Diabetes.