MR/PET Motion Correction from Coil Fingerprints

项目总结： 该方案致力于开发、临床实施和评估一种新型的实时、 用于并行MR/PET采集的运动校正方法。可用的数据采集方法和 MR/PET扫描仪中的重建不能充分利用 市面上可买到的MR/PET仪器。这些能力可以用来获得实时 用于减少PET图像中的运动伪影和部分体积偏差的信息，而不显著 影响了相应核磁共振检查的工作流程。我们的方法建立在以下方面的记录之上 多机构研究团队，负责MRI和PET数据采集和重建的方方面面。这个 建议的方法将提高PET扫描的灵敏度和定量准确性 在MR/PET检查过程中同时获得。这样的改进将带来更好的 检测、分期和监测腹部小病变(&lt；1 cm)，目前评估有限 由于运动模糊和部分体积偏差造成的信号损失过大。

PROJECT SUMMARY: This proposal is devoted to the development, clinical implementation and evaluation of a novel, real-time, motion correction methodology for concurrent MR/PET acquisitions. Available methods for data acquisition and reconstruction in MR/PET scanners do not fully capitalize on the simultaneous imaging capabilities of the commercially available MR/PET instrumentation. These capabilities could be used to obtain real-time information for reducing motion artifacts and partial voluming bias from PET images without significantly affecting the workflow of the corresponding MRI examination. Our methodology builds on the track record of the multi-institutional research team with all aspects of MRI and PET data acquisition and reconstruction. The proposed methodology will lead to improved sensitivity and quantitative accuracy for PET scans when they are simultaneously acquired during the course of an MR/PET examination. Such improvements will lead to better detection, staging and surveillance of small (<1cm) abdominal lesions, which assessment is currently limited due to excessive signal loss from motion blur and partial voluming bias.