MR/PET Motion Correction from Coil Fingerprints

项目概要： 该提案致力于开发，临床实施和评价一种新的，实时的， 用于并行MR/PET采集的运动校正方法。数据采集的可用方法， MR/PET扫描仪中的重建不能完全利用MR/PET扫描仪的同时成像能力。 市售MR/PET仪器。这些功能可以用来获得实时 用于减少PET图像的运动伪影和部分体积偏移的信息， 影响相应MRI检查的工作流程。我们的方法建立在跟踪记录的基础上， 多机构研究团队，拥有MRI和PET数据采集和重建的各个方面。的 所提出的方法将提高PET扫描的灵敏度和定量准确性， 在MR/PET检查过程中同时采集。这些改进将带来更好的 检测、分期和监测腹部小病灶（<1 cm），目前评估有限 这是由于来自运动模糊和部分体积偏移的过度信号损失。

PROJECT SUMMARY: This proposal is devoted to the development, clinical implementation and evaluation of a novel, real-time, motion correction methodology for concurrent MR/PET acquisitions. Available methods for data acquisition and reconstruction in MR/PET scanners do not fully capitalize on the simultaneous imaging capabilities of the commercially available MR/PET instrumentation. These capabilities could be used to obtain real-time information for reducing motion artifacts and partial voluming bias from PET images without significantly affecting the workflow of the corresponding MRI examination. Our methodology builds on the track record of the multi-institutional research team with all aspects of MRI and PET data acquisition and reconstruction. The proposed methodology will lead to improved sensitivity and quantitative accuracy for PET scans when they are simultaneously acquired during the course of an MR/PET examination. Such improvements will lead to better detection, staging and surveillance of small (<1cm) abdominal lesions, which assessment is currently limited due to excessive signal loss from motion blur and partial voluming bias.