Administrative Core

行政核心

基本信息

项目摘要

Project Summary This Administrative Core will provide the necessary scientific, organization, and fiscal oversight for the Consortium for Immunotherapeutics Against Emerging Viral Threats. This Consortium includes multiple investigators who will conduct studies involving a large array of antibodies, cell lines, biochemical and cell-based assays, animal models and machine learning techniques that will be critical for developing effective therapeutics for alphaviruses, arenaviruses, and filoviruses. An essential feature of the consortium is the coordination of projects and studies on these antibodies and resources to minimize duplication of efforts and maximize integration of the separate multidisciplinary analyses. The Administrative Core will develop and implement a management plan to ensure the success of this program. The Core will continuously monitor the scientific progress of each program component, as well as ensure that results are collated and interpreted, and that subsequent action steps are effectively communicated to the entire group at each stage of the study. The Core will also facilitate communications with the Center, NIH, and the larger research community, as well as our external advisors to promote effective translation of results toward the development of products and clinical applications. The Core will manage financial resources and ensure that select agent, vertebrate animal, human subject, and intellectual property issues are respected, that data are deposited, and resources shared with the scientific community. The Core will also initiate all external collaboration and oversee invitation, selection, and progress of Supplemental Research activities as directed by the NIH. Furthermore, the Core includes a Clinical Consultant who will advise on the translation of research findings to small clinical trials.
项目总结

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Erica Ollmann Saphire其他文献

Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae
  • DOI:
    10.1007/s00705-012-1454-0
  • 发表时间:
    2012-09-23
  • 期刊:
  • 影响因子:
    2.500
  • 作者:
    Jens H. Kuhn;Yiming Bao;Sina Bavari;Stephan Becker;Steven Bradfute;J. Rodney Brister;Alexander A. Bukreyev;Kartik Chandran;Robert A. Davey;Olga Dolnik;John M. Dye;Sven Enterlein;Lisa E. Hensley;Anna N. Honko;Peter B. Jahrling;Karl M. Johnson;Gary Kobinger;Eric M. Leroy;Mark S. Lever;Elke Mühlberger;Sergey V. Netesov;Gene G. Olinger;Gustavo Palacios;Jean L. Patterson;Janusz T. Paweska;Louise Pitt;Sheli R. Radoshitzky;Erica Ollmann Saphire;Sophie J. Smither;Robert Swanepoel;Jonathan S. Towner;Guido van der Groen;Viktor E. Volchkov;Victoria Wahl-Jensen;Travis K. Warren;Manfred Weidmann;Stuart T. Nichol
  • 通讯作者:
    Stuart T. Nichol
A global collaboration for systematic analysis of broad-ranging antibodies against the SARS-CoV-2 spike protein
针对 SARS-CoV-2 刺突蛋白的广泛抗体的系统分析的全球合作
  • DOI:
    10.1016/j.celrep.2025.115499
  • 发表时间:
    2025-04-22
  • 期刊:
  • 影响因子:
    6.900
  • 作者:
    Sharon L. Schendel;Xiaoying Yu;Peter J. Halfmann;Jarjapu Mahita;Brendan Ha;Kathryn M. Hastie;Haoyang Li;Daniel Bedinger;Camille Troup;Kan Li;Natalia Kuzmina;Jordi B. Torrelles;Jennifer E. Munt;Melissa Mattocks;Mary Osei-Twum;Heather M. Callaway;The CoVIC-DB Team;Stephen Reece;Anne Palser;Paul Kellam;S. Moses Dennison;Erica Ollmann Saphire
  • 通讯作者:
    Erica Ollmann Saphire
The C-terminus of Sudan ebolavirus VP40 contains a functionally important CXsubn/subC motif, a target for redox modifications
苏丹埃博拉病毒 VP40 的 C 末端包含一个功能重要的 CXC 基序,这是氧化还原修饰的一个靶点。
  • DOI:
    10.1016/j.str.2023.06.004
  • 发表时间:
    2023-09-07
  • 期刊:
  • 影响因子:
    4.300
  • 作者:
    Anke-Dorothee Werner;Martin Schauflinger;Michael J. Norris;Michael Klüver;Anna Trodler;Astrid Herwig;Christina Brandstädter;Melissa Dillenberger;Gerhard Klebe;Andreas Heine;Erica Ollmann Saphire;Katja Becker;Stephan Becker
  • 通讯作者:
    Stephan Becker
Infusion of neutralization into Lassa vaccine design
将中和作用注入拉沙疫苗设计中
  • DOI:
    10.1016/j.it.2025.05.006
  • 发表时间:
    2025-07-01
  • 期刊:
  • 影响因子:
    13.900
  • 作者:
    Haoyang Li;Kathryn M. Hastie;Erica Ollmann Saphire
  • 通讯作者:
    Erica Ollmann Saphire
Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop.
人类免疫缺陷病毒 1 型 gp120 V3 环的重复构象。
  • DOI:
    10.1016/s0042-6822(03)00525-7
  • 发表时间:
    2003
  • 期刊:
  • 影响因子:
    3.7
  • 作者:
    R. Stanfield;J. Ghiara;Erica Ollmann Saphire;A. Profy;I. Wilson
  • 通讯作者:
    I. Wilson

Erica Ollmann Saphire的其他文献

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{{ truncateString('Erica Ollmann Saphire', 18)}}的其他基金

Structure of the SARS-CoV-2 Nucleocapsid: building block to viral capsid
SARS-CoV-2 核衣壳的结构:病毒衣壳的构建模块
  • 批准号:
    10728253
  • 财政年份:
    2023
  • 资助金额:
    $ 31.99万
  • 项目类别:
Integrative Immunogen Design and Testing
综合免疫原设计和测试
  • 批准号:
    10842890
  • 财政年份:
    2021
  • 资助金额:
    $ 31.99万
  • 项目类别:
Consortium for Immunotherapeutics against Emerging Viral Threats
针对新兴病毒威胁的免疫治疗联盟
  • 批准号:
    10447562
  • 财政年份:
    2021
  • 资助金额:
    $ 31.99万
  • 项目类别:
Integrative Immunogen Design and Testing
综合免疫原设计和测试
  • 批准号:
    10328121
  • 财政年份:
    2021
  • 资助金额:
    $ 31.99万
  • 项目类别:
Consortium for Immunotherapeutics against Emerging Viral Threats
针对新兴病毒威胁的免疫治疗联盟
  • 批准号:
    10199909
  • 财政年份:
    2020
  • 资助金额:
    $ 31.99万
  • 项目类别:
Specific and Broadly Active Monoclonal Antibody Therapeutics Against The Filoviruses
针对丝状病毒的特异性且广泛活性的单克隆抗体疗法
  • 批准号:
    10402338
  • 财政年份:
    2019
  • 资助金额:
    $ 31.99万
  • 项目类别:
Consortium for Immunotherapeutics against Emerging Viral Threats
针对新兴病毒威胁的免疫治疗联盟
  • 批准号:
    9924443
  • 财政年份:
    2019
  • 资助金额:
    $ 31.99万
  • 项目类别:
Specific and Broadly Active Monoclonal Antibody Therapeutics Against The Filoviruses
针对丝状病毒的特异性且广泛活性的单克隆抗体疗法
  • 批准号:
    10158448
  • 财政年份:
    2019
  • 资助金额:
    $ 31.99万
  • 项目类别:
Specific and Broadly Active Monoclonal Antibody Therapeutics Against The Filoviruses
针对丝状病毒的特异性且广泛活性的单克隆抗体疗法
  • 批准号:
    10617736
  • 财政年份:
    2019
  • 资助金额:
    $ 31.99万
  • 项目类别:
Administrative Core
行政核心
  • 批准号:
    10617743
  • 财政年份:
    2019
  • 资助金额:
    $ 31.99万
  • 项目类别:

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出血性中风后动物模型中神经血管变化的量化
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