Inflammatory Mechanisms Linking Sleep Disturbances and Cognitive Deficits in Schizophrenia in Later Life
Inflammatory Mechanisms Linking Sleep Disturbances and Cognitive Deficits in Schizophrenia in Later Life
批准号:
10159125
负责人:
Ellen Eun-Ok Lee
金额:
$20.13万
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-05-07 至 2024-04-30
关键词:
AccountingAddressAffectAgeAgingAntipsychotic AgentsAttentionBehaviorBioinformaticsBiologicalBody mass indexC-reactive proteinCell CountCellsChronicChronic DiseaseClinicalCognitionCognitiveCognitive deficitsComplexConsensusDataDevelopmentDietDimensionsDoseElderlyFutureGene ExpressionGene Expression ProfilingGeneral PopulationGenomicsGoalsImmuneImpaired cognitionIncidenceIndividualInflammationInflammatoryInterleukin-6InterventionInvestigationK-Series Research Career ProgramsLeadLinkLongitudinal StudiesMeasuresMediatingMediator of activation proteinMental DepressionMental disordersModelingNational Institute of Mental HealthPathway interactionsPatient Self-ReportPerformancePersonsPhysical activityPittsburgh Sleep Quality IndexReportingResearchRisk FactorsSample SizeSchizophreniaScientistSeveritiesSleepSleep DisordersSleep disturbancesSleeplessnessSmokingTestingTimeTrainingUnited States National Institutes of HealthVulnerable PopulationsWomanactigraphyage relatedbasecareercognitive functioncognitive performancecostexecutive functionfollow-upgeriatric mental healthhigh riskimprovedimproved functioningindexinginflammatory markerlifestyle factorsmenmiddle agemodifiable riskmolecular markerpoor sleeppromoterrecruitsexskillssleep qualitytranscription factortranslational physician
中文摘要
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英文摘要
SUMMARY/ABSTRACT
The proposed K23 application will strongly support Ellen Lee, MD’s long-term career goal of becoming an independent clinical-translational physician-scientist in geriatric mental health. This project investigates inflammatory mechanisms underlying sleep and cognition in middle-aged and older adults (41-70 years old) with schizophrenia (SZ). The proposal has considerable
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Inflammatory Mechanisms Linking Sleep Disturbances and Cognitive Deficits in Schizophrenia in Later Life
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批准号:10405005
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项目类别:
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资助金额:$20.04万
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财政年份:2019
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负责人:Ellen Eun-Ok Lee
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依托单位:
Inflammatory Mechanisms Linking Sleep Disturbances and Cognitive Deficits in Schizophrenia in Later Life
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批准号:9926924
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项目类别:
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资助金额:$20.26万
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财政年份:2019
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负责人:Ellen Eun-Ok Lee
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依托单位:
Inflammatory Mechanisms Linking Sleep Disturbances and Cognitive Deficits in Schizophrenia in Later Life
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批准号:10597117
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项目类别:
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资助金额:$20.25万
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财政年份:2019
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负责人:Ellen Eun-Ok Lee
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依托单位:
海外基金