Administrative Core

行政核心

• 批准号: 10161686
• 负责人: Oscar L. Lopez
• 金额: $ 27.93万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-15 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10161686
• 关键词: Address; Administrator; Advisory Committees; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Animals; Area; Biological; Biological Markers; Biology; Biology of Aging; Blood; Budgets; Caregiver support; Caring; Clinical; Clinical Data; Clinical Drug Development; Clinical Research; Clinical Trials; Collaborations; Communication; Communities; Complex; Critiques; DNA; Data; Data Science; Data Set; Data Storage and Retrieval; Databases; Dementia; Dementia with Lewy Bodies; Detection; Development; Developmental Process; Discipline; Disease; Education; Ensure; Epidemiology; Expenditure; Faculty; Fostering; Functional disorder; Funding; Genetic; Genetic Diseases; Geriatrics; Goals; Grant; Health Sciences; Health care facility; Image; Inflammation; Infrastructure; Inherited; International; Leadership; Ligands; Link; Maintenance; Monitor; Multicenter Studies; National Institute on Aging; Neurobiology; Neurology; Neurosciences; Pathologic; Pharmaceutical Technology; Philanthropic Fund; Physiology; Pilot Projects; Policies; Positron-Emission Tomography; Postdoctoral Fellow; Psychiatry; Recommendation; Regulation; Reproducibility; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Resources; Sampling; Schedule; Schools; Site; Structure; Supervision; Synapses; System; Systems Biology; Technology; Testing; Tissues; Training; Training Programs; Universities; Work; aging brain; base; blood-based biomarker; cerebral amyloidosis; cohesion; data exchange; data management; data repository; data sharing; design; drug discovery; education research; human subject; improved; interest; interoperability; medical schools; medically underserved; meetings; minimally invasive; minority communities; multidisciplinary; neurogenetics; neuroimaging; neuropathology; novel; operation; organizational structure; outreach; peripheral blood; pre-clinical; pre-doctoral; prevent; programs; public-private partnership; recruit; repository; research study; statistics; tau Proteins; underserved community; usability

Core A: Administrative Core: Summary/Abstract: The University of Pittsburgh Alzheimer’s Disease Research Center (PITT-ADRC) Administrative (ADM) Core provides the organization and structure for planning and implementation of ADRC core and research activities. The core supervises all PITT-ADRC functions and the Clinical, Data Management & Statistics, Neuropathology, Biomarker and Neurogenetics, Neuroimaging, and Outreach, Engagement and Education Cores, as well as the Research and Education Component. The ADM Core monitors budgets to ensure fiscal responsibility; organizes the review and funding process for the Developmental Projects and for the philanthropically funded pilot studies. It monitors all PITT-ADRC research projects utilizing ADRC subjects or resources. This core determines new research directions, including the recruitment of new investigators to work in AD. Establishment of outreach efforts to the medically underserved and minority communities are directed and stimulated by the Core. The Core also oversees participation in multicenter studies, data transfer to NIA databases, tissue and DNA samples to NIA repositories, cross-ADC collaborations, and other national and international initiatives. Through the establishment of a comprehensive communications system the Core Leaders, investigators, and staff maintain an integrated, coherent and multidisciplinary focus. The goals of the ADM Core are achieved by the Executive Committee, which is comprised of the Director, Co-Director, Advisory Co-Director, Center Administrator, and Core and Project Leaders. It is aided in these tasks by advice of the Internal and External Advisory Committees, which is chaired by the Senior Vice Chancellor/Dean of the Medical School, and includes the Chairmen of Psychiatry and Neurology Departments, and the former Chair of Epidemiology at the University of Pittsburgh. They provide guidance on policy, administration, and scientific direction, as well as ensure that all schools of the Health Sciences and facilities of the University of Pittsburgh provide full cooperation in the execution of ADRC activities. The External Advisory Board is comprised of nationally respected researchers and clinicians with expertise in disciplines relevant to AD. They provide scientific critiques of research and operations of the PITT-ADRC, as well as recommendations for new initiatives. The ADM Core coordinates a well-established research infrastructure that will serve to the local, national, and international scientific community. We anticipate that the ADM Core will continue improving the ADRC data distribution. We have an exemplary record of data sharing and collaboration.

核心A：管理核心：摘要/摘要： 匹兹堡大学阿尔茨海默氏病 研究中心（PITT-ADRC）行政（ADM）核心提供了计划的组织和结构 以及ADRC核心和研究活动的实施。核心监督所有PITT-ADRC功能和 临床，数据管理和统计，神经病理学，生物标志物和神经遗传学，神经影像学， 以及外展，参与和教育核心以及研究和教育部分。这 ADM核心监视预算以确保财政责任；组织审核和资金流程 发展项目和慈善资助的试点研究。它监视所有Pitt-ADRC研究 使用ADRC主题或资源的项目。该核心决定了新的研究方向，包括 招募新研究人员从事广告。建立向医学不足的宣传工作 少数民族社区是由核心指示和刺激的。核心也在海外参与 多中心研究，数据转移到NIA数据库，组织和DNA样品到NIA存储库，交叉ADC 合作以及其他国家和国际倡议。通过建立全面的 通信系统核心领导者，调查人员和员工保持综合，连贯和 多学科重点。 ADM核心的目标是由执行委员会实现的，该委员会已完成，该委员会已完成。 联合导演，咨询主任，中心管理员以及核心和项目负责人。它在这些方面得到了帮助 通过内部和外部咨询委员会的建议，由高级副副主席主持 医学院的总理/院长，包括精神病学和神经病学部门主席， 以及匹兹堡大学流行病学的前主席。他们提供政策指导， 行政和科学方向，并确保健康科学和设施的所有学校 匹兹堡大学在执行ADRC活动方面提供了充分的合作。外部咨询 董事会由具有与与学科有关的专业知识的国家尊敬的研究人员和临床医生组成 广告。它们提供了Pitt-Adrc的研究和运营的科学批判性，以及 新计划的建议。 ADM核心协调一个公认的研究基础设施，该基础设施将用于当地，国家， 和国际科学界。我们预计ADM核心将继续改善ADRC 数据分布。我们有数据共享和协作的典范记录。