Precision Health Intervention Methodology Training in Self-Management of Multiple Chronic Conditions

项目概要/摘要： 美国正在经历快速的宏观社会转型;人口老龄化， 变得更加多样化。人口老龄化需要更多的护理;多种慢性疾病的频率和负担 （MCC）正在快速增长。最近由精准医学引发的健康范式转变 倡议，沿着计算科学、人工智能和移动的/可穿戴设备的重大进步 技术，现在提供了重要的机会，通过发展自我管理科学， 针对个人的策略。不仅基于遗传学，还基于心理社会表型 特点，目前的社会和技术变革的步伐需要一个全面的，结构化的， 跨学科的方法，自我管理的研究培训，为下一代的护士科学家。 德克萨斯大学奥斯汀分校的护理学院在培养未来的护士方面具有独特的优势 科学家谁可以开发有效的个性化干预解决自我的复杂需求， 管理MCC患者。位于得克萨斯州奥斯汀的“卫生技术中心”， 在全国最具活力的跨学科健康研究环境之一，我们很好 定位于培养未来的科学家在精确的健康方法，解决MCC为重点的自我， 管理科学学校目前经营着两个强大的卓越中心，专注于 为得不到充分服务的人口进行自我管理和健康促进方面的跨学科研究。我们也 与四个活跃的T32培训项目（人口科学， 跨学科神经科学，生物医学工程和医学信息学，以及大数据科学）在UT- 奥斯汀促进高影响力，跨学科的研究培训，为所有学员在这四个项目。到 利用我们合作研究的势头，充分利用我们的教育资源，我们建议 一个新的博士培训计划（NIH T32），以提供未来的护士科学家（13名博士前和6名博士后 5年以上的受训人员），掌握关键技能和知识，以开发和实施创新、有效和 为患有MCC的人群提供个性化干预措施。 这一跨学科培训计划的具体目标是：（1）为学员提供 尖端的知识和方法，为患有糖尿病的人构建精确，个性化的干预措施。 MCC;（2）利用整个大学和社区的资源，确保跨学科的培训， 培养创造性的，成功的临床研究者，他们将对推进自我发展产生重大影响， 管理科学通过精确的健康方法;（3）提升现有的优势， 大学的学院，互动，跨学科的研究环境，通过创建一个国家模式， 培训具有精准健康专业知识的护士科学家。

Project Summary /Abstract: The U.S. is undergoing rapid macrosocial transformations; the population is growing older and becoming more diverse. An aging population needs more care; the frequency and burden of multiple chronic conditions (MCC) are rapidly increasing. The recent health paradigm shift initiated by the Precision Medicine Initiative, along with significant advances in computational science, artificial intelligence, and mobile/wearable technology, now offers important opportunities to advance self-management science through the development of strategies tailored to the individual level. Based not only on genetics but also psychosocial phenotypic characteristics, the current pace of social and technological change demands a comprehensive, structured, transdisciplinary approach to self-management research training for the next generation of nurse scientists. The University of Texas at Austin’s School of Nursing is uniquely positioned to foster future nurse scientists who can develop effective personalized interventions addressing the complex needs of self- management for people with MCC. Located at the “epicenter of the health technology hub” in Austin, Texas, within one of the most vibrant transdisciplinary health research environments in the nation, we are well positioned to train future scientists in precision health methodologies addressing MCC-focused self- management science. The school currently operates two strong centers for excellence focusing on transdisciplinary research in self-management and health promotion for underserved populations. We also have established collaborative agreements with four active T32 training programs (population science, interdisciplinary neuroscience, biomedical engineering and medical informatics, and big data science) at UT- Austin to facilitate high impact, transdisciplinary research training for all trainees in these four programs. To capitalize on our momentum of collaborative research and maximize our educational resources, we propose a new PhD training program (NIH T32) to provide future nurse scientists (13 pre-doctoral and 6 post-doctoral trainees over 5 years) with critical skills and knowledge to develop and implement innovative, effective and personalized interventions for populations suffering from MCCs. The specific objectives of this transdisciplinary training program are: (1) To provide trainees with cutting edge knowledge and methods for constructing precise, personalized interventions for people with MCCs; (2) to utilize resources throughout our university and community to ensure training across disciplines to develop creative, successful clinical investigators who will make a major impact on advancing self- management science through precision health methodology; (3) to elevate the existing strengths of the university’s collegial, interactive, interdisciplinary research environment by creating a national model for training nurse scientists with precision health expertise.