The Johns Hopkins Baltimore-Washington-India Clinical Trials Unit (BWI CTU)
The Johns Hopkins Baltimore-Washington-India Clinical Trials Unit (BWI CTU)
批准号:
10165945
负责人:
Charles W. Flexner
金额:
$46.07万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
已结题
起止时间:
2020-06-25 至 2021-11-30
关键词:
2019-nCoVAIDS clinical trial groupAcuteAddressAdultAdult Respiratory Distress SyndromeAnti-Infective AgentsAzithromycinBaltimoreCOVID-19Cessation of lifeClinicalClinical ResearchClinical TrialsClinical Trials Support UnitClinical Trials UnitCodeCollaborationsCommunicable DiseasesCommunitiesCommunity Health EducationCommunity OutreachConduct Clinical TrialsConsentCoronavirusCoughingCountyDiseaseEducationElderlyEnsureEnvironmentEquipmentFeverGrantHIVHIV Vaccine Trials NetworkHealthHealth systemHigh PrevalenceHome environmentHospitalizationHuman Subject ResearchHydroxychloroquineImmune responseImmunizationIndiaInfectionInfection ControlInfrastructureInpatientsInstitutionLaboratoriesLower Respiratory Tract InfectionMedicalMedicineMonoclonal AntibodiesOutpatientsParticipantPatient RecruitmentsPatientsPersonsPneumoniaPopulationPreventionPrevention ResearchPrevention trialProceduresProcessResearchResearch PersonnelResourcesRiskSafetySiteSore ThroatSupport SystemSymptomsTechniquesTestingTherapeuticTrainingUniversitiesVaccinesViral hepatitisVirusVisitWalkersWashingtonclinical research sitecommunity settingcoronavirus diseasedesignexperienceflexibilityhigh riskimplementation researchinfection riskinnovationinterestinvestigator trainingmembermetropolitanoutpatient facilityoutreachpandemic diseasepathogenpreventrecruitrespiratorytherapy developmenttreatment researchvaccine developmentvaccine evaluation
中文摘要
SARS-CoV-2是一种冠状病毒,已成为全球大流行的主要原因
英文摘要
SARS-CoV-2 is a coronavirus that has emerged as a major cause of pandemic upper and lower
respiratory tract infection, progressing in approximately 15-20% of infected persons to severe
pneumonia that can be complicated by adult respiratory distress syndrome (ARDS) and, in 1-
3% of infected persons, death. Collectively, respiratory and systemic illness due to this virus is
referred to as Coronavirus Disease 2019 (COVID-19). SARS-CoV-2 infection also manifests
with relatively mild symptoms such as cough, sore throat, and fever, or with no symptoms
(asymptomatic infection). Persons with a mild or asymptomatic infection have been implicated
in the spread of this highly infectious virus in the community. Efficient, safe, and rigorous
research and clinical trials are essential to the development of interventions that can treat and
prevent COVID-19 infection. The Baltimore-Washington-India Clinical Trials Unit (BWI CTU)
supports high quality HIV-related treatment and prevention research at two domestic Clinical
Research Sites (CRS's) in Baltimore and Washington. The Johns Hopkins University Clinical
Research Site (JHU CRS) in Baltimore, and the Whitman Walker Health (WWH) CRS in
Washington, DC, have highly experienced and innovative leaders in anti-infective research and
have a long and successful record of HIV and viral hepatitis clinical research implementation.
The health systems that are supported by JHU and our partner institutions currently provide
medical coverage for more than half of all adult residents in the state. This includes having a
physical presence in every major population center in the state, including the metropolitan
Washington, DC, counties -- where nearly half of the state's cases have occurred. This gives us
unprecedented access to those with or at risk of this infection. JHU is also home to the Center
for Immunization Research, a renowned resource for clinical vaccine development and
evaluation. We have been invited by the HPTN and HVTN to serve as a site for SARS-CoV-2
vaccine and monoclonal antibody prevention trials. COVID-19 clinical research provides special
challenges beyond the processes developed for most traditional infectious diseases clinical
research. This supplement will allow our sites to prepare to offer high quality COVID-related
clinical research sponsored by DAIDS Networks, and enhance the protection of investigators
and research participants at JHU and WWH.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Long-Acting/Extended Release Antiretroviral Resource Program (LEAP)
-
批准号:8920992
-
项目类别:
-
资助金额:$42.55万
-
财政年份:2015
-
负责人:Charles W. Flexner
-
依托单位:
The Long-Acting/Extended Release Antiretroviral Resource Program (LEAP)
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批准号:10653140
-
项目类别:
-
资助金额:$82.87万
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财政年份:2015
-
负责人:Charles W. Flexner
-
依托单位:
Long-Acting/Extended Release Antiretroviral Resource Program (LEAP)
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批准号:9064082
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项目类别:
-
资助金额:$48.53万
-
财政年份:2015
-
负责人:Charles W. Flexner
-
依托单位:
The Long-Acting/Extended Release Antiretroviral Resource Program (LEAP)
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批准号:10218050
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项目类别:
-
资助金额:$70.96万
-
财政年份:2015
-
负责人:Charles W. Flexner
-
依托单位:
The Long-Acting/Extended Release Antiretroviral Resource Program (LEAP)
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批准号:10431973
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项目类别:
-
资助金额:$68.75万
-
财政年份:2015
-
负责人:Charles W. Flexner
-
依托单位:
The Long-Acting/Extended Release Antiretroviral Resource Program (LEAP)
-
批准号:10079160
-
项目类别:
-
资助金额:$76.4万
-
财政年份:2015
-
负责人:Charles W. Flexner
-
依托单位:
Johns Hopkins AIDS Clinical Trials Unit
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批准号:7903668
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项目类别:
-
资助金额:$141.33万
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财政年份:2009
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负责人:Charles W. Flexner
-
依托单位:
Johns Hopkins AIDS Clinical Trials Unit
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批准号:7096301
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项目类别:
-
资助金额:$103.49万
-
财政年份:2007
-
负责人:Charles W. Flexner
-
依托单位:
Johns Hopkins University Baltimore India Clinical Trail Unit (JHUBI CTU)
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批准号:10304148
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项目类别:
-
资助金额:$208.27万
-
财政年份:2007
-
负责人:Charles W. Flexner
-
依托单位:
Johns Hopkins AIDS Clinical Trials Unit
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批准号:7993586
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项目类别:
-
资助金额:$134.63万
-
财政年份:2007
-
负责人:Charles W. Flexner
-
依托单位:
Johns Hopkins AIDS Clinical Trials Unit
-
批准号:8402556
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项目类别:
-
资助金额:$103.81万
-
财政年份:2007
-
负责人:Charles W. Flexner
-
依托单位:
Johns Hopkins University Baltimore India Clinical Trail Unit (JHUBI CTU)
-
批准号:10531597
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项目类别:
-
资助金额:$209.92万
-
财政年份:2007
-
负责人:Charles W. Flexner
-
依托单位:
Johns Hopkins University Baltimore India Clinical Trail Unit (JHUBI CTU)
-
批准号:10057666
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项目类别:
-
资助金额:$200.26万
-
财政年份:2007
-
负责人:Charles W. Flexner
-
依托单位:
Johns Hopkins AIDS Clinical Trials Unit
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批准号:7560001
-
项目类别:
-
资助金额:$160.34万
-
财政年份:2007
-
负责人:Charles W. Flexner
-
依托单位:
Johns Hopkins AIDS Clinical Trials Unit
-
批准号:8197295
-
项目类别:
-
资助金额:$169.81万
-
财政年份:2007
-
负责人:Charles W. Flexner
-
依托单位:
Johns Hopkins AIDS Clinical Trials Unit
-
批准号:7348412
-
项目类别:
-
资助金额:$138.84万
-
财政年份:2007
-
负责人:Charles W. Flexner
-
依托单位:
Johns Hopkins AIDS Clinical Trials Unit
-
批准号:7615344
-
项目类别:
-
资助金额:$6.91万
-
财政年份:2007
-
负责人:Charles W. Flexner
-
依托单位:
Johns Hopkins AIDS Clinical Trials Unit
-
批准号:7743417
-
项目类别:
-
资助金额:$104.81万
-
财政年份:2007
-
负责人:Charles W. Flexner
-
依托单位:
ACTG 362
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批准号:7604533
-
项目类别:
-
资助金额:$0.31万
-
财政年份:2006
-
负责人:Charles W. Flexner
-
依托单位:
ACTG A5128
-
批准号:7604555
-
项目类别:
-
资助金额:$0.46万
-
财政年份:2006
-
负责人:Charles W. Flexner
-
依托单位:
海外基金