AIDS Clinical Trial Group Laboratory Center

艾滋病临床试验组实验室中心

基本信息

项目摘要

ABSTRACT The AIDS Clinical Trials Group (ACTG) has been at the forefront of clinical research to advance HIV therapeutics and improve the health of patients living with HIV/AIDS for over 30 years. Rigorous scientific research conducted by the ACTG has laid the cornerstones for current HIV treatment guidelines. In this application for the competitive renewal of the ACTG Network Laboratory Center, we propose a transformative laboratory research agenda that draws on an international consortium of prominent clinical and laboratory investigators in collaboration with a world-class Statistical and Data Management Center to conduct leading edge laboratory research, testing, assay development and laboratory training for the support of innovative interventional clinical trials. The ACTG Network Laboratory Center will improve scientific knowledge and technical capability by providing state-of-the-art laboratory support in the four NIH/DAIDS priority areas: antiretroviral therapy (ART) free HIV remission, 2) novel therapeutics targeting HIV, 3) tuberculosis, and 4) HIV co-morbidities, including neurologic complications and hepatitis B cure. The continued expansion of an effective, quality-assured laboratory program at domestic and international sites for protocol safety measures, state-of-the-art assays for virology and tuberculosis, immunology and biomarkers, pharmacology, and genomics will provide the essential framework for advancing the scientific agenda of the ACTG Network. The Laboratory Center will continue to provide oversight of established specimen and human DNA repositories for the ACTG Network, harmonize specific laboratory testing and standardized operating procedures with other networks, where feasible, and support the laboratory training of technologists and investigators domestically and internationally.
摘要

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Grace M Aldrovandi其他文献

Immunomodulatory factors in cervicovaginal secretions from pregnant and non-pregnant women: A cross-sectional study
孕妇和非孕妇宫颈阴道分泌物中的免疫调节因子:横断面研究
  • DOI:
  • 发表时间:
    2011
  • 期刊:
  • 影响因子:
    3.7
  • 作者:
    Jan Walter;Linda Fraga;Melanie J Orin;William D Decker;Theresa Gipps;Alice Stek;Grace M Aldrovandi
  • 通讯作者:
    Grace M Aldrovandi

Grace M Aldrovandi的其他文献

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{{ truncateString('Grace M Aldrovandi', 18)}}的其他基金

Core C -Centralized Laboratory Support Core
核心C - 集中实验室支持核心
  • 批准号:
    10609765
  • 财政年份:
    2022
  • 资助金额:
    --
  • 项目类别:
Study of Tecovirimat for Human Monkeypox Virus (STOMP)
Tecovirimat 针对人猴痘病毒 (STOMP) 的研究
  • 批准号:
    10689623
  • 财政年份:
    2022
  • 资助金额:
    --
  • 项目类别:
Core C -Centralized Laboratory Support Core
核心C - 集中实验室支持核心
  • 批准号:
    10458372
  • 财政年份:
    2022
  • 资助金额:
    --
  • 项目类别:
A5401 COVID Supplement
A5401 新冠肺炎补充剂
  • 批准号:
    10203227
  • 财政年份:
    2020
  • 资助金额:
    --
  • 项目类别:
Effects of Human Milk Oligosaccharides and Gut Microbiome on Growth and Morbidity in HIV-Exposed Uninfected Infants
母乳低聚糖和肠道微生物组对暴露于 HIV 的未感染婴儿生长和发病的影响
  • 批准号:
    9920737
  • 财政年份:
    2019
  • 资助金额:
    --
  • 项目类别:
Effects of Human Milk Oligosaccharides and Gut Microbiome on Growth and Morbidity in HIV-Exposed Uninfected Infants
母乳低聚糖和肠道微生物组对暴露于 HIV 的未感染婴儿生长和发病的影响
  • 批准号:
    10610833
  • 财政年份:
    2019
  • 资助金额:
    --
  • 项目类别:
Effects of Human Milk Oligosaccharides and Gut Microbiome on Growth and Morbidity in HIV-Exposed Uninfected Infants
母乳低聚糖和肠道微生物组对暴露于 HIV 的未感染婴儿生长和发病的影响
  • 批准号:
    10382305
  • 财政年份:
    2019
  • 资助金额:
    --
  • 项目类别:
Maturation, Infectibility, and Trauma(MIT) Contributes to HIV Susceptibility in Adolescents
成熟、传染性和创伤(麻省理工学院)导致青少年对艾滋病毒的易感性
  • 批准号:
    9245320
  • 财政年份:
    2017
  • 资助金额:
    --
  • 项目类别:
International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Laboratory Center
国际孕产妇儿科青少年艾滋病临床试验(IMPAACT)实验室中心
  • 批准号:
    9317270
  • 财政年份:
    2016
  • 资助金额:
    --
  • 项目类别:
International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Laboratory Center
国际孕产妇儿科青少年艾滋病临床试验(IMPAACT)实验室中心
  • 批准号:
    9188522
  • 财政年份:
    2016
  • 资助金额:
    --
  • 项目类别:

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