Auditory & Integrative Functions of the Prefrontal Cortex DIVERSITY SUPPLEMENT

总结 在这个多元化的补充，我们建议一年的研究和培训的候选人 在丽莎贝丝·罗曼斯基博士的实验室里进行研究三个实验 提出了在补充实验1中，候选人将检查媒体的作用 前额叶皮层在性能监控和错误检测中的作用。为此，他将训练受试者 来完成一个更难的视听工作记忆任务。这将允许 在错误和增加难度的过程中检查神经活动。在实验2中， 候选人将使用Oddball任务来确定腹侧前额叶集合如何检测 不一致的视听刺激对。使用这个易于培训的任务将允许测试 比传统的工作记忆模式更多的刺激对。在实验3中， 面孔发声通信刺激的时间绑定将通过改变 SOA的听觉和视觉组件，并记录腹侧的预期变化 前额叶神经元的联系这些研究的结果将告诉我们， 前额叶皮层在检测和整合交流信息的特定特征方面的作用 这与刺激的上下文相关性和时间的重要性直接相关， 声音信息和相关的嘴部运动的关系。实验是合乎逻辑的 父母补助金的扩展，是一种有效的方法，以获得更多的信息， 我们的实验室里已经有了宝贵的资源。

SUMMARY In this diversity supplement we are proposing a year of research and training for the candidate to perform research in the laboratory of Dr. Lizabeth Romanski. Three experiments are proposed. In supplemental experiment 1, the candidate will examine the role of the medial prefrontal cortex in performance monitoring and error detection. To do this he will train subjects to perform a more difficult version of the audiovisual working memory task. This will allow for the examination of the neural activity during errors and increased difficulty. In Experiment 2, the candidate will use the Oddball task to determine how ventral prefrontal ensembles detect incongruent audiovisual pairs of stimuli. Use of this easy-to-train task will allow the testing of many more stimulus pairs than traditional working memory paradigms. In Experiment 3, the temporal binding of face-vocalization communication stimuli will be examined by altering the SOA of the auditory and visual components and recording the expected change in ventral prefrontal neurons to these asynchronies. The results of these studies will inform us of the role of prefrontal cortex in detecting and integrating specific features of communication information that are directly related to contextual relevance of stimuli and the importance of the temporal relationship of vocal information and associated mouth movements. The experiments are logical extensions of the parent grant and are an efficient approach to gaining more information from valuable resources already in place in our laboratory.