Midcareer Investigator Award in Patient-Oriented Research K24

项目总结/摘要 这是大卫·图罗克博士职业中期研究者奖的重新提交申请- 导向研究。图罗克博士的全球目标是：1）通过以下措施降低美国的意外怀孕率： 大幅度提高所有妇女和家庭获得计划生育护理的质量和机会，2）提供 科学数据支持减少意外怀孕的做法，3）作为榜样， 指导致力于以患者为导向的研究的初级研究人员。他的成功研究 * 帮助妇女获得高效可逆避孕（HER-C）的创新方法，包括宫内避孕 避孕装置（IUD）和避孕植入物。在犹他州大学，他担任NICHD的研究中心PI。 避孕临床试验网络，在计划生育奖学金的共同主任，和PI为他的 资助了R 01，支持两种宫内节育器用于紧急避孕的RCT。他指导着一个庞大的 来自多个学科的临床研究者骨干。这个应用程序描述了职业发展， 指导和研究活动，将在未来五年内执行的保护时间提供 K24获奖该应用的研究基础是盐湖高效可逆 避孕倡议-盐湖（HER盐湖）。这一创新的社区范围内的计划将评估 消除HER-C障碍以及利用电子技术的长期社会、健康和经济影响 媒体教育，以增加HER-C摄取。这个以病人为导向的研究项目将发生在一个环境中， 医疗补助覆盖范围有限，没有国家计划生育医疗补助豁免。它将作为一个平台， 完成职业发展目标和学员从事指导临床研究的环境， 走向成功独立的职业道路Turok博士将完成以下职业生涯 本项目期间的发展目标：1）扩大他对人口医学的知识，2） 提高指导技能; 3）加强传播科学成果的能力。这些活动将 扩大Turok博士的指导范围，因为他在五年的奖励期内指导了十几名研究人员。 他有足够的机会，通过他的工作与妇女的健康研究人员在他的部门， 驻地研究主任，与初级教师在他的部门作为导师通过BIRCWH和 WRHR计划，整个机构作为犹他州KL 2初级教师大学的共同主任 辅导计划，并通过家庭协会与全国各地的计划生育研究人员 规划通过提供工资支持，K24奖将使Turok博士能够显着扩大他的活跃 指导角色和富有成效的面向患者的研究。总的来说，这些科学和职业发展 目标将消除障碍，并改善使用，宫内节育器和避孕植入物，以减少3百万 美国每年意外怀孕。

Project Summary/Abstract This is a resubmission application for Dr. David Turok's Midcareer Investigator Award in Patient- Oriented Research. Dr. Turok's global aims are to 1) reduce the U.S. rate of unintended pregnancy by significantly improving the quality of, and access to, family planning care for all women and families, 2) provide scientific data supporting practices that reduce unintended pregnancy, and 3) serve as a role model for, and mentor to, junior investigators devoted to patient-oriented research. His successful research addresses innovative ways to help women access highly effective reversible contraception (HER-C), including intrauterine devices (IUDs) and contraceptive implants. At the University of Utah he serves as the site-PI for the NICHD's Contraceptive Clinical Trial Network, the co-Director of the Fellowship in Family Planning, and the PI for his funded R01 supporting a RCT of two IUDs for emergency contraception. He mentors a large and growing cadre of clinical investigators from several disciplines. This application describes career development, mentoring, and research activities that would be executed in the next five years under protected time afforded by a K24 award. The research foundation of this application is the Salt Lake Highly Effective Reversible Contraception Initiative - Salt Lake (HER Salt Lake). This innovative community-wide program will assess the long-term social, health, and economic impacts of removing barriers to HER-C as well as by utilizing electronic media education to increase HER-C uptake. This patient-oriented research project will occur in an environment with limited Medicaid coverage and no state family planning Medicaid waiver. It will serve as a platform to accomplish career development goals and a setting for trainees to engage in mentored clinical research on their path towards successful, independent careers. Dr. Turok will accomplish the following career development goals during this project period: 1) expand his knowledge of population-based medicine, 2) improve his mentoring skills, and 3) strengthen his ability to disseminate scientific results. These activities will expand Dr. Turok's mentoring reach as he mentors over a dozen researchers over the five-year award period. He has ample access to mentees through his work with women's health researchers in his department as the director of resident research, with junior faculty in his Department as a mentor through the BIRCWH and WRHR programs, throughout the institution as the co-Director of the University of Utah KL2 junior faculty mentoring program, and with family planning researchers throughout the country via the Society of Family Planning. By providing salary support, the K24 award would enable Dr. Turok to significantly expand his active mentoring roles and productive patient-oriented research. Overall, these scientific and career development aims will remove barriers to, and improve use of, IUDs and contraceptive implants to decrease the 3 million U.S. unintended pregnancies each year.