Mentoring Emerging Scientists for Careers in Substance Use Research

摘要 这是加州大学旧金山分校的续签申请，旨在延长一项为期五年的研究 临床研究人员的教育计划(成瘾和多样化的早期职业学习-领导)。这个 该计划继续其使命，为代表不足的早期研究科学家提供培训 种族/少数民族群体，旨在增加进行行为行为的种族/少数民族人数 或药理物质使用障碍的治疗研究。领先建立在国家的平台上 药物滥用治疗临床试验网络(CTN)，一个由科学家和医疗保健组织组成的网络， 为基于科学的疗法的多点测试提供广泛的基础设施。在未来五年，我们将 扩大招聘范围，将博士后研究员(而不仅仅是助理教授级别的参与者)包括在 努力接触到更多有前途的早期调查人员。培训计划将包括一个新的 实施科学培训的组成部分，以使学者的研究技能与 NIDA CTN在初级保健和其他普通医疗领域进行严格的多点临床试验的优先事项 设置。培训计划极大地受益于与培训计划和教职员工的紧密联系 在加州大学旧金山分校进行临床研究，并出席加州大学临床与翻译科学 研究所。具体目标是：1)将实习学者与CTN的资深科学家相匹配，后者将提供 科学指导和专业指导；2)为学者提供支持，开展试点研究 NIH后续申请的途径；3)帮助学者发展赠款撰写技能，目标是 在领导培训期间提交竞争激烈的NIH申请；4)提供文化剪裁培训 循证治疗和实施研究方法；5)为学者提供知识和 解决临床试验中遇到的伦理、法规和项目管理问题的技能；以及6)培养 与物质使用障碍临床试验中的顶尖专家建立关系的网络结构 研究。学者将参加为期3年的培训，包括每年4周的暑期强化课程。 在加州大学旧金山分校举办研讨会和讲习班，在学年期间进行指导和培训，并参与 CTN全国研究和培训会议。学者将与NIDA CTN高级调查人员匹配 世卫组织将在为期3年的培训期内指导他们。成功获得美国国立卫生研究院研究或事业奖 发展是参与该计划的学者计划好的可衡量的结果。该计划 解决对具有文化能力的物质使用方面的专业知识的调查人员的需求 有可能影响医疗保健政策和实践的疾病治疗研究。长期目标 增加人数不足的种族/少数族裔群体吸食毒品的个人资料 障碍治疗研究。

ABSTRACT This is a renewal application from the University of California, San Francisco to extend a five-year research education program for clinical researchers (Learning for Early Careers in Addiction and Diversity-LEAD). The program continues its mission to provide training to early-stage research scientists from underrepresented racial/ethnic minority groups, aiming to increase the number of racial/ethnic minorities who conduct behavioral or pharmacological substance use disorders treatment research. LEAD builds on the platform of the National Drug Abuse Treatment Clinical Trials Network (CTN), a network of scientists and healthcare organizations that offers a broad infrastructure for multisite testing of science-based therapies. During the next five years, we will expand recruitment to include postdoctoral fellows (rather than just assistant professor level participants) in an effort to reach a larger pool of promising early stage investigators. The training program will include a new component in implementation science training to align and strengthen scholars' research skills with the priorities of the NIDA CTN to conduct rigorous multisite clinical trials in primary care and other general medical settings. The training program greatly benefits from strong connections to training programs and faculty conducting clinical research at UCSF and the presence of the UCSF Clinical and Translational Science Institute. Specific aims are to: 1) Match trainee scholars with senior scientists in the CTN who will provide scientific mentoring and professional guidance; 2) provide scholars with support to conduct pilot research as a pathway to subsequent NIH applications; 3) assist scholars in developing grant-writing skills, with the goal of submitting competitive NIH applications during the LEAD training period; 4) offer training in cultural tailoring of evidence-based treatments and implementation research methods; 5) provide scholars with knowledge and skills to address ethical, regulatory, and project management issues encountered in clinical trials; and 6) foster a networking structure to build relationships with leading experts in substance use disorder clinical trials research. Scholars will participate in a 3-year training, consisting of a yearly 4-week summer intensive program of seminars and workshops at UCSF, mentoring and training during the academic year, and participation in CTN national research and training meetings. Scholars will be matched with NIDA CTN senior investigators who will mentor them through the 3-year training period. A successful NIH award for research or career development is the planned measurable outcome for the scholars who participate in the program. The program addresses the need for investigators who have expertise in conducting culturally-competent substance use disorder treatment research that has the potential to impact healthcare policy and practice. The long-term goal to increase the number of PIs from underrepresented racial/ethnic minority groups conducting substance use disorder treatment research.