Behavioral Sleep Medicine: Training in Sleep and Aging

行为睡眠医学：睡眠与衰老训练 摘要 目标：在这项建议中，迈克尔·佩利斯博士请求支持：1)稳定和扩大他对朱尼尔的指导 行为睡眠医学领域和生物心理社会研究领域的研究人员 失眠(病因、病理生理学、治疗结果研究和治疗作用机制 学习)；2)参与一项教育活动计划，为他和他的导师提供强大的 评估衰老是失眠研究的调节因素的基础；以及3)建立 与初级研究人员合作网络，在他的NIA支持下进行假设驱动的研究 关于失眠的自然历史的项目。背景：佩利斯博士一直致力于以病人为本 S从20岁中期开始研究。他一直是非凡导师的受益者，并一直发扬光大 这一传统贯穿了他整个职业生涯。他对失眠症的研究从基础研究扩展到 以病人为中心的研究。资格要求：应聘者有丰富的私人助理、助理助理或助理助理经验 多个NIH奖项，以及通过NIH K23和R21机制指导他人的成功记录。 环境：宾夕法尼亚大学(宾夕法尼亚大学)是睡眠和时间生物学的主要中心之一 研究和临床工作。因此，它可以为PI和他的实习生提供很多东西。发展活动： 导师专业发展的核心活动将是实施每月研讨会 专注于睡眠和衰老的系列节目。顶尖科学家将被邀请到宾夕法尼亚大学与他们讨论他们的想法 关于衰老对睡眠需求、睡眠能力和睡眠机会的影响以及 这些领域增加了睡眠障碍和不良健康后果的风险。此外， 导师/PI每年将参加一次研讨会或课程，重点是从生物心理社会角度看待老龄化和 一个与生物伦理学有关的讲习班。指导计划：担任宾夕法尼亚大学行为睡眠医学部主任 计划，Perlis博士创建了一套独特的教育活动，吸引了广泛的受训者 包括资深专业人员、初级调查人员、博士后研究员、研究生和医学生， 本科毕业生和本科生。K24的计划是为学员提供一套教育 活动包括专业发展、行为睡眠医学方面的重点培训和深入的 对睡眠连续性的量化评估(例如，睡眠日记评估， 动作图、PSG和qEEG)。研究：候选人提议创建协作网络进行 与Jr.的档案分析。研究人员使用他的NIA支持失眠数据库的自然历史 (R01AG041783)。被邀请的个人将拥有除PI之外的专业领域，因此将作为 为PI提供了既教又学的机会。将在该奖项的第三年举行一次会议，会上 合作者将以小组形式介绍和讨论他们的数据。意义：这款K24将支持Perlis博士 他为下一代提供以病人为导向的研究培训的努力。

BEHAVIORAL SLEEP MEDICINE: TRAINING IN SLEEP & AGING ABSTRACT Goals: In this proposal, Dr. Michael Perlis requests support to: 1) stabilize and expand his mentoring of junior investigators in the domain of behavioral sleep medicine and in the biopsychosocial approach to the study of insomnia (etiology, pathophysiology, treatment outcome research, and treatment mechanisms of action studies); 2) engage a program of educational activities that will provide him and his mentees with a strong foundation for the assessment of aging as a moderating factor for insomnia research; and 3) establish a collaborative network with junior investigators to conduct hypothesis-driven research with his NIA supported project on the natural history of insomnia. Background: Dr. Perlis has been involved in patient-oriented research since his mid-20's. He has been the beneficiary of exceptional mentorship and has carried forward this tradition over the entirety of his career. His research on Insomnia Disorder extends from basic research to patient-oriented research. Qualifications: The candidate has extensive experience as a PI, Co-PI, or Co-I on multiple NIH awards and a successful track record in mentoring others via NIH K23 and R21 mechanisms. Environment: The University of Pennsylvania (Penn) is one of the premier centers for sleep and chronobiology research and clinical work. As such, it has much to offer both the PI and his trainees. Development Activities: The core activity for the mentor's professional development will be the implementation of a monthly seminar series focused on Sleep and Aging. Leading scientists will be invited to Penn to discuss their ideas with respect to the effects of aging on sleep need, sleep ability and sleep opportunity and how alterations within these domains confer increased risk for sleep disorders and adverse health outcomes. In addition, the mentor/PI will take one workshop or course per year focused on biopsychosocial perspectives on aging and one workshop pertaining to bioethics. Mentoring Program: As the Director of Penn's Behavioral Sleep Medicine program, Dr. Perlis has created a unique set of educational activities that attract a wide array of trainees including established professionals, junior investigators, post-doctoral fellows, graduate and medical students, post baccalaureates, and undergraduates. The plan for this K24 is to provide trainees with a set of educational activities that include professional development, focused training in behavioral sleep medicine, and an in-depth appreciation regarding the quantitative assessment of sleep continuity (e.g., sleep diary assessments, actigraphy, PSG, & QEEG). Research: The candidate proposes to create a collaborative network to conduct archival analysis with Jr. Investigators using his NIA supported natural history of insomnia databases (R01AG041783). The individuals invited will have specialty areas apart from the PI, and thus will serve as an opportunity for the PI to both teach and learn. A conference will be held in the 3rd year of the award at which the collaborators will present and discuss their data as a group. Significance: This K24 will support Dr. Perlis in his efforts to provide patient-oriented research training to the next generation.